Tenascin-R (TN-R) (Janusin) (Restrictin)
1_MGADG 6_ ETVVL 11_ KNMLI 16_ GINLI 21_ LLGSM 26_ IKPSE 31_ CQLEV 36_ TTERV 41_ QRQSV 46_ EEEGG 51_ IANYN 56_ TSSKE 61_ QPVVF 66_ NHVYN 71_ INVPL 76_ DNLCS 81_ SGLEA 86_ SAEQE 91_ VSAED 96_ ETLAE 101_ YMGQT 106_ SDHES 111_ QVTFT 116_ HRINF 121_ PKKAC 126_ PCASS 131_ AQVLQ 136_ ELLSR 141_ IEMLE 146_ REVSV 151_ LRDQC 156_ NANCC 161_ QESAA 166_ TGQLD 171_ YIPHC 176_ SGHGN 181_ FSFES 186_ CGCIC 191_ NEGWF 196_ GKNCS 201_ EPYCP 206_ LGCSS 211_ RGVCV 216_ DGQCI 221_ CDSEY 226_ SGDDC 231_ SELRC 236_ PTDCS 241_ SRGLC 246_ VDGEC 251_ VCEEP 256_ YTGED 261_ CRELR 266_ CPGDC 271_ SGKGR 276_ CANGT 281_ CLCEE 286_ GYVGE 291_ DCGQR 296_ QCLNA 301_ CSGRG 306_ QCEEG 311_ LCVCE 316_ EGYQG 321_ PDCSA 326_ VAPPE 331_ DLRVA 336_ GISDR 341_ SIELE 346_ WDGPM 351_ AVTEY 356_ VISYQ 361_ PTALG 366_ GLQLQ 371_ QRVPG 376_ DWSGV 381_ TITEL 386_ EPGLT 391_ YNISV 396_ YAVIS 401_ NILSL 406_ PITAK 411_ VATHL 416_ STPQG 421_ LQFKT 426_ ITETT 431_ VEVQW 436_ EPFSF 441_ SFDGW 446_ EISFI 451_ PKNNE 456_ GGVIA 461_ QVPSD 466_ VTSFN 471_ QTGLK 476_ PGEEY 481_ IVNVV 486_ ALKEQ 491_ ARSPP 496_ TSASV 501_ STVID 506_ GPTQI 511_ LVRDV 516_ SDTVA 521_ FVEWI 526_ PPRAK 531_ VDFIL 536_ LKYGL 541_ VGGEG 546_ GRTTF 551_ RLQPP 556_ LSQYS 561_ VQALR 566_ PGSRY 571_ EVSVS 576_ AVRGT 581_ NESDS 586_ ATTQF 591_ TTEID 596_ APKNL 601_ RVGSR 606_ TATSL 611_ DLEWD 616_ NSEAE 621_ VQEYK 626_ VVYST 631_ LAGEQ 636_ YHEVL 641_ VPRGI 646_ GPTTR 651_ ATLTD 656_ LVPGT 661_ EYGVG 666_ ISAVM 671_ NSQQS 676_ VPATM 681_ NARTE 686_ LDSPR 691_ DLMVT 696_ ASSET 701_ SISLI 706_ WTKAS 711_ GPIDH 716_ YRITF 721_ TPSSG 726_ IASEV 731_ TVPKD 736_ RTSYT 741_ LTDLE 746_ PGAEY 751_ IISVT 756_ AERGR 761_ QQSLE 766_ STVDA 771_ FTGFR 776_ PISHL 781_ HFSHV 786_ TSSSV 791_ NITWS 796_ DPSPP 801_ ADRLI 806_ LNYSP 811_ RDEEE 816_ EMMEV 821_ SLDAT 826_ KRHAV 831_ LMGLQ 836_ PATEY 841_ IVNLV 846_ AVHGT 851_ VTSEP 856_ IVGSI 861_ TTGID 866_ PPKDI 871_ TISNV 876_ TKDSV 881_ MVSWS 886_ PPVAS 891_ FDYYR 896_ VSYRP 901_ TQVGR 906_ LDSSV 911_ VPNTV 916_ TEFTI 921_ TRLNP 926_ ATEYE 931_ ISLNS 936_ VRGRE 941_ ESERI 946_ CTLVH 951_ TAMDN 956_ PVDLI 961_ ATNIT 966_ PTEAL 971_ LQWKA 976_ PVGEV 981_ ENYVI 986_ VLTHF 991_ AVAGE 996_ TILVD 1001_ GVSEE 1006_ FRLVD 1011_ LLPST 1016_ HYTAT 1021_ MYATN 1026_ GPLTS 1031_ GTIST 1036_ NFSTL 1041_ LDPPA 1046_ NLTAS 1051_ EVTRQ 1056_ SALIS 1061_ WQPPR 1066_ AEIEN 1071_ YVLTY 1076_ KSTDG 1081_ SRKEL 1086_ IVDAE 1091_ DTWIR 1096_ LEGLL 1101_ ENTDY 1106_ TVLLQ 1111_ AAQDT 1116_ TWSSI 1121_ TSTAF 1126_ TTGGR 1131_ VFPHP 1136_ QDCAQ 1141_ HLMNG 1146_ DTLSG 1151_ VYPIF 1156_ LNGEL 1161_ SQKLQ 1166_ VYCDM 1171_ TTDGG 1176_ GWIVF 1181_ QRRQN 1186_ GQTDF 1191_ FRKWA 1196_ DYRVG 1201_ FGNVE 1206_ DEFWL 1211_ GLDNI 1216_ HRITS 1221_ QGRYE 1226_ LRVDM 1231_ RDGQE 1236_ AAFAS 1241_ YDRFS 1246_ VEDSR 1251_ NLYKL 1256_ RIGSY 1261_ NGTAG 1266_ DSLSY 1271_ HQGRP 1276_ FSTED 1281_ RDNDV 1286_ AVTNC 1291_ AMSYK 1296_ GAWWY 1301_ KNCHR 1306_ TNLNG 1311_ KYGES 1316_ RHSQG 1321_ INWYH 1326_ WKGHE 1331_ FSIPF 1336_ VEMKM 1341_ RPYNH 1346_ RLMAG 1351_RKRQS
1: Neural extracellular matrix (ECM) protein involved in interactions with different cells and matrix components. These interactions can influence cellular behavior by either evoking a stable adhesion and differentiation, or repulsion and inhibition of neurite growth. Binding to cell surface gangliosides inhibits RGD-dependent integrin-mediated cell adhesion and results in an inhibition of PTK2/FAK1 (FAK) phosphorylation and cell detachment. Binding to membrane surface sulfatides results in a oligodendrocyte adhesion and differentiation. Interaction with CNTN1 induces a repulsion of neurons and an inhibition of neurite outgrowth. Interacts with SCN2B may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier. TNR-linked chondroitin sulfate glycosaminoglycans are involved in the interaction with FN1 and mediate inhibition of cell adhesion and neurite outgrowth. The highly regulated addition of sulfated carbohydrate structure may modulate the adhesive properties of TNR over the course of development and during synapse maintenance (By similarity)