Fibroblast growth factor 13 (FGF-13) (Fibroblast growth factor homologous factor 2) (FHF-2)
1_MAAAI 6_ ASSLI 11_ RQKRQ 16_ ARERE 21_ KSNAC 26_ KCVSS 31_ PSKGK 36_ TSCDK 41_ NKLNV 46_ FSRVK 51_ LFGSK 56_ KRRRR 61_ RPEPQ 66_ LKGIV 71_ TKLYS 76_ RQGYH 81_ LQLQA 86_ DGTID 91_ GTKDE 96_ DSTYT 101_ LFNLI 106_ PVGLR 111_ VVAIQ 116_ GVQTK 121_ LYLAM 126_ NSEGY 131_ LYTSE 136_ LFTPE 141_ CKFKE 146_ SVFEN 151_ YYVTY 156_ SSMIY 161_ RQQQS 166_ GRGWY 171_ LGLNK 176_ EGEIM 181_ KGNHV 186_ KKNKP 191_ AAHFL 196_ PKPLK 201_ VAMYK 206_ EPSLH 211_ DLTEF 216_ SRSGS 221_ GTPTK 226_ SRSVS 231_ GVLNG 236_GKSMS
1: Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules (By similarity). Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching (By similarity). Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus (By similarity). Regulates voltage-gated sodium channel transport and function (PubMed:15282281, PubMed:33245860, PubMed:36696443). May also play a role in MAPK signaling (By similarity). Required for the development of axonal initial segment-targeting inhibitory GABAergic synapses made by chandelier neurons (By similarity)