Fetal and adult testis-expressed transcript protein (Cancer/testis antigen 43) (CT43) (Tumor antigen BJ-HCC-2)
1_MAGGP 6_ PNTKA 11_ EMEMS 16_ LAEEL 21_ NHGRQ 26_ GENQE 31_ HLVIA 36_ EMMEL 41_ GSRSR 46_ GASQK 51_ KQKLE 56_ QKAAG 61_ SASAK 66_ RVWNM 71_ TATRP 76_ KKMGS 81_ QLPKP 86_ RMLRE 91_ SGHGD 96_ AHLQE 101_ YAGNF 106_ QGIRF 111_ HYDRN 116_ PGTDA 121_ VAQTS 126_ LEEFN 131_ VLEME 136_ VMRRQ 141_ LYAVN 146_ RRLRA 151_ LEEQG 156_ ATWRH 161_ RETLI 166_ IAVLV 171_ SASIA 176_NLWLW
1: Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER-mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis (PubMed:27402544). May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling (PubMed:26567849)