Gene name: MYDGF

Uniprot entry:

Q969H8

Protein names:

Myeloid-derived growth factor (MYDGF)

Protein sequence:

1_MAAPS 6_ GGWNG 11_ VGASL 16_ WAALL 21_ LGAVA 26_ LRPAE 31_ AVSEP 36_ TTVAF 41_ DVRPG 46_ GVVHS 51_ FSHNV 56_ GPGDK 61_ YTCMF 66_ TYASQ 71_ GGTNE 76_ QWQMS 81_ LGTSE 86_ DHQHF 91_ TCTIW 96_ RPQGK 101_ SYLYF 106_ TQFKA 111_ EVRGA 116_ EIEYA 121_ MAYSK 126_ AAFER 131_ ESDVP 136_ LKTEE 141_ FEVTK 146_ TAVAH 151_ RPGAF 156_ KAELS 161_ KLVIV 166_AKASR

Protein annotations

Protein functions:

1: Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway (By similarity). Involved in endothelial cell proliferation and angiogenesis (PubMed:25581518)