Sodium-coupled neutral amino acid transporter 4 (Amino acid transporter A3) (Na(+)-coupled neutral amino acid transporter 4) (Solute carrier family 38 member 4) (System A amino acid transporter 3) (System N amino acid transporter 3)
1_MDPME 6_ LRNVN 11_ IEPDD 16_ ESSSG 21_ ESAPD 26_ SYIGI 31_ GNSEK 36_ AAMSS 41_ QFANE 46_ DTESQ 51_ KFLTN 56_ GFLGK 61_ KKLAD 66_ YADEH 71_ HPGTT 76_ SFGMS 81_ SFNLS 86_ NAIMG 91_ SGILG 96_ LSYAM 101_ ANTGI 106_ ILFII 111_ MLLAV 116_ AILSL 121_ YSVHL 126_ LLKTA 131_ KEGGS 136_ LIYEK 141_ LGEKA 146_ FGWPG 151_ KIGAF 156_ VSITM 161_ QNIGA 166_ MSSYL 171_ FIIKY 176_ ELPEV 181_ IRAFM 186_ GLEEN 191_ TGEWY 196_ LNGNY 201_ LIIFV 206_ SVGII 211_ LPLSL 216_ LKNLG 221_ YLGYT 226_ SGFSL 231_ TCMVF 236_ FVSVV 241_ IYKKF 246_ QIPCP 251_ LPVLD 256_ HSVGN 261_ LSFNN 266_ TLPMH 271_ VVMLP 276_ NNSES 281_ SDVNF 286_ MMDYT 291_ HRNPA 296_ GLDEN 301_ QAKGS 306_ LHDSG 311_ VEYEA 316_ HSDDK 321_ CEPKY 326_ FVFNS 331_ RTAYA 336_ IPILV 341_ FAFVC 346_ HPEVL 351_ PIYSE 356_ LKDRS 361_ RRKMQ 366_ TVSNI 371_ SITGM 376_ LVMYL 381_ LAALF 386_ GYLTF 391_ YGEVE 396_ DELLH 401_ AYSKV 406_ YTLDI 411_ PLLMV 416_ RLAVL 421_ VAVTL 426_ TVPIV 431_ LFPIR 436_ TSVIT 441_ LLFPK 446_ RPFSW 451_ IRHFL 456_ IAAVL 461_ IALNN 466_ VLVIL 471_ VPTIK 476_ YIFGF 481_ IGASS 486_ ATMLI 491_ FILPA 496_ VFYLK 501_ LVKKE 506_ TFRSP 511_ QKVGA 516_ LIFLV 521_ VGIFF 526_ MIGSM 531_ ALIII 536_ DWIYD 541_PPNSK
1: Symporter that cotransports neutral amino acids and sodium ions from the extraccellular to the intracellular side of the cell membrane (PubMed:11342143, PubMed:19015196, PubMed:33928121). The transport is electrogenic, pH dependent and partially tolerates substitution of Na(+) by Li(+) (PubMed:11414754). Preferentially transports smaller amino acids, such as glycine, L-alanine, L-serine, L-asparagine and L-threonine, followed by L-cysteine, L-histidine, L-proline and L-glutamine and L-methionine (PubMed:11414754, PubMed:33928121)