U7 snRNA-associated Sm-like protein LSm10
1_MAVSH 6_ SVKER 11_ TISEN 16_ SLIIL 21_ LQGLQ 26_ GRVTT 31_ VDLRD 36_ ESVAH 41_ GRIDN 46_ VDAFM 51_ NIRLA 56_ KVTYT 61_ DRWGH 66_ QVKLD 71_ DLFVT 76_ GRNVR 81_ YVHIP 86_ DDVNI 91_ TSTIE 96_ QQLQI 101_ IHRVR 106_ NFGGK 111_ GQGRW 116_EFPPK
1: Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases. Binds specifically to U7 snRNA. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner