Gene name: PPP2R3C

Uniprot entry:

Q969Q6

Protein names:

Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma (Protein phosphatase subunit G5PR) (Rhabdomyosarcoma antigen MU-RMS-40.6A/6C)

Protein sequence:

1_MDWKE 6_ VLRRR 11_ LATPN 16_ TCPNK 21_ KKSEQ 26_ ELKDE 31_ EMDLF 36_ TKYYS 41_ EWKGG 46_ RKNTN 51_ EFYKT 56_ IPRFY 61_ YRLPA 66_ EDEVL 71_ LQKLR 76_ EESRA 81_ VFLQR 86_ KSREL 91_ LDNEE 96_ LQNLW 101_ FLLDK 106_ HQTPP 111_ MIGEE 116_ AMINY 121_ ENFLK 126_ VGEKA 131_ GAKCK 136_ QFFTA 141_ KVFAK 146_ LLHTD 151_ SYGRI 156_ SIMQF 161_ FNYVM 166_ RKVWL 171_ HQTRI 176_ GLSLY 181_ DVAGQ 186_ GYLRE 191_ SDLEN 196_ YILEL 201_ IPTLP 206_ QLDGL 211_ EKSFY 216_ SFYVC 221_ TAVRK 226_ FFFFL 231_ DPLRT 236_ GKIKI 241_ QDILA 246_ CSFLD 251_ DLLEL 256_ RDEEL 261_ SKESQ 266_ ETNWF 271_ SAPSA 276_ LRVYG 281_ QYLNL 286_ DKDHN 291_ GMLSK 296_ EELSR 301_ YGTAT 306_ MTNVF 311_ LDRVF 316_ QECLT 321_ YDGEM 326_ DYKTY 331_ LDFVL 336_ ALENR 341_ KEPAA 346_ LQYIF 351_ KLLDI 356_ ENKGY 361_ LNVFS 366_ LNYFF 371_ RAIQE 376_ LMKIH 381_ GQDPV 386_ SFQDV 391_ KDEIF 396_ DMVKP 401_ KDPLK 406_ ISLQD 411_ LINSN 416_ QGDTV 421_ TTILI 426_ DLNGF 431_ WTYEN 436_ REALV 441_ ANDSE 446_NSADL

Protein annotations

Protein functions:

1: May regulate MCM3AP phosphorylation through phosphatase recruitment (By similarity). May act as a negative regulator of ABCB1 expression and function through the dephosphorylation of ABCB1 by TFPI2/PPP2R3C complex (PubMed:24333728). May play a role in the activation-induced cell death of B-cells (By similarity)