UDP-xylose and UDP-N-acetylglucosamine transporter (Solute carrier family 35 member B4) (YEA4 homolog)
1_MRPAL 6_ AVGLV 11_ FAGCC 16_ SNVIF 21_ LELLA 26_ RKHPG 31_ CGNIV 36_ TFAQF 41_ LFIAV 46_ EGFLF 51_ EADLG 56_ RKPPA 61_ IPIRY 66_ YAIMV 71_ TMFFT 76_ VSVVN 81_ NYALN 86_ LNIAM 91_ PLHMI 96_ FRSGS 101_ LIANM 106_ ILGII 111_ ILKKR 116_ YSIFK 121_ YTSIA 126_ LVSVG 131_ IFICT 136_ FMSAK 141_ QVTSQ 146_ SSLSE 151_ NDGFQ 156_ AFVWW 161_ LLGIG 166_ ALTFA 171_ LLMSA 176_ RMGIF 181_ QETLY 186_ KRFGK 191_ HSKEA 196_ LFYNH 201_ ALPLP 206_ GFVFL 211_ ASDIY 216_ DHAVL 221_ FNKSE 226_ LYEIP 231_ VIGVT 236_ LPIMW 241_ FYLLM 246_ NIITQ 251_ YVCIR 256_ GVFIL 261_ TTECA 266_ SLTVT 271_ LVVTL 276_ RKFVS 281_ LIFSI 286_ LYFQN 291_ PFTLW 296_ HWLGT 301_ LFVFI 306_ GTLMY 311_ TEVWN 316_ NLGTT 321_ KSEPQ 326_KDSKK
1: Antiporter that transports nucleotide sugars across the endoplasmic reticulum (ER) membrane in exchange for another nucleotide sugar. May couple UDP-alpha-D-glucuronate (UDP-GlcA) or UDP-alpha-D-xylose (UDP-Xyl) efflux to UDP-alpha-D-glucuronate (UDP-GlcA) influx into the ER lumen, which in turn stimulates glucuronidation and excretion of endobiotics and xenobiotics
2: Has UDP-GlcA:UDP-GlcNAc antiporter activity
3: Has UDP-GlcA:UDP-GlcNAc antiporter activity