Gene name: TMEM203

Uniprot entry:

Q969S6

Protein names:

Transmembrane protein 203

Protein sequence:

1_MLFSL 6_ RELVQ 11_ WLGFA 16_ TFEIF 21_ VHLLA 26_ LLVFS 31_ VLLAL 36_ RVDGL 41_ VPGLS 46_ WWNVF 51_ VPFFA 56_ ADGLS 61_ TYFTT 66_ IVSVR 71_ LFQDG 76_ EKRLA 81_ VLRLF 86_ WVLTV 91_ LSLKF 96_ VFEML 101_ LCQKL 106_ AEQTR 111_ ELWFG 116_ LITSP 121_ LFILL 126_ QLLMI 131_RACRV

Protein annotations

Protein functions:

1: Involved in the regulation of cellular calcium homeotasis (PubMed:25996873). Required for spermatogenesis (PubMed:25996873). Acts as a regulator of STING-mediated inflammatory signaling in macrophages (PubMed:31346090). Forms a complex with STING, promoting the activity of TBK1 kinase and the transcription factor IRF3, leading to activation of type I interferon expression (By similarity)