7-methylguanosine phosphate-specific 5'-nucleotidase (7-methylguanosine nucleotidase) (EC 3.1.3.91) (Cytosolic 5'-nucleotidase 3B) (Cytosolic 5'-nucleotidase III-like protein) (cN-III-like protein) (EC 3.1.3.5) (N(7)-methylguanylate 5'-phosphatase)
1_MAEEV 6_ STLMK 11_ ATVLM 16_ RQPGR 21_ VQEIV 26_ GALRK 31_ GGGDR 36_ LQVIS 41_ DFDMT 46_ LSRFA 51_ YNGKR 56_ CPSSY 61_ NILDN 66_ SKIIS 71_ EECRK 76_ ELTAL 81_ LHHYY 86_ PIEID 91_ PHRTV 96_ KEKLP 101_ HMVEW 106_ WTKAH 111_ NLLCQ 116_ QKIQK 121_ FQIAQ 126_ VVRES 131_ NAMLR 136_ EGYKT 141_ FFNTL 146_ YHNNI 151_ PLFIF 156_ SAGIG 161_ DILEE 166_ IIRQM 171_ KVFHP 176_ NIHIV 181_ SNYMD 186_ FNEDG 191_ FLQGF 196_ KGQLI 201_ HTYNK 206_ NSSAC 211_ ENSGY 216_ FQQLE 221_ GKTNV 226_ ILLGD 231_ SIGDL 236_ TMADG 241_ VPGVQ 246_ NILKI 251_ GFLND 256_ KVEER 261_ RERYM 266_ DSYDI 271_ VLEKD 276_ ETLDV 281_ VNGLL 286_ QHILC 291_QGVQL
1: Specifically hydrolyzes 7-methylguanosine monophosphate (m(7)GMP) to 7-methylguanosine and inorganic phosphate (PubMed:23223233, PubMed:24603684). The specific activity for m(7)GMP may protect cells against undesired salvage of m(7)GMP and its incorporation into nucleic acids (PubMed:23223233). Also has weak activity for CMP (PubMed:23223233, PubMed:24603684). UMP and purine nucleotides are poor substrates (PubMed:23223233)