tRNA modification GTPase GTPBP3, mitochondrial (GTP-binding protein 3) (Mitochondrial GTP-binding protein 1)
1_MWRGL 6_ WTLAA 11_ QAARG 16_ PRRLC 21_ TRRSS 26_ GAPAP 31_ GSGAT 36_ IFALS 41_ SGQGR 46_ CGIAV 51_ IRTSG 56_ PASGH 61_ ALRIL 66_ TAPRD 71_ LPLAR 76_ HASLR 81_ LLSDP 86_ RSGEP 91_ LDRAL 96_ VLWFP 101_ GPQSF 106_ TGEDC 111_ VEFHV 116_ HGGPA 121_ VVSGV 126_ LQALG 131_ SVPGL 136_ RPAEA 141_ GEFTR 146_ RAFAN 151_ GKLNL 156_ TEVEG 161_ LADLI 166_ HAETE 171_ AQRRQ 176_ ALRQL 181_ DGELG 186_ HLCRG 191_ WAETL 196_ TKALA 201_ HVEAY 206_ IDFGE 211_ DDNLE 216_ EGVLE 221_ QADIE 226_ VRALQ 231_ VALGA 236_ HLRDA 241_ RRGQR 246_ LRSGV 251_ HVVVT 256_ GPPNA 261_ GKSSL 266_ VNLLS 271_ RKPVS 276_ IVSPE 281_ PGTTR 286_ DVLET 291_ PVDLA 296_ GFPVL 301_ LSDTA 306_ GLREG 311_ VGPVE 316_ QEGVR 321_ RARER 326_ LEQAD 331_ LILAM 336_ LDASD 341_ LASPS 346_ SCNFL 351_ ATVVA 356_ SVGAQ 361_ SPSDS 366_ SQRLL 371_ LVLNK 376_ SDLLS 381_ PEGPG 386_ PGPDL 391_ PPHLL 396_ LSCLT 401_ GEGLD 406_ GLLEA 411_ LRKEL 416_ AAVCG 421_ DPSTD 426_ PPLLT 431_ RARHQ 436_ HHLQG 441_ CLDAL 446_ GHYKQ 451_ SKDLA 456_ LAAEA 461_ LRVAR 466_ GHLTR 471_ LTGGG 476_ GTEEI 481_ LDIIF 486_QDFCV
1: GTPase component of the GTPBP3-MTO1 complex that catalyzes the 5-taurinomethyluridine (taum(5)U) modification at the 34th wobble position (U34) of mitochondrial tRNAs (mt-tRNAs), which plays a role in mt-tRNA decoding and mitochondrial translation (PubMed:29390138, PubMed:33619562). Taum(5)U formation on mammalian mt-tRNA requires the presence of both GTPBP3-mediated GTPase activity and MTO1 catalytic activity (PubMed:29390138)