Gene name: PPP1R14A

Uniprot entry:

Q96A00

Protein names:

Protein phosphatase 1 regulatory subunit 14A (17 kDa PKC-potentiated inhibitory protein of PP1) (Protein kinase C-potentiated inhibitor protein of 17 kDa) (CPI-17)

Protein sequence:

1_MAAQR 6_ LGKRV 11_ LSKLQ 16_ SPSRA 21_ RGPGG 26_ SPGGL 31_ QKRHA 36_ RVTVK 41_ YDRRE 46_ LQRRL 51_ DVEKW 56_ IDGRL 61_ EELYR 66_ GMEAD 71_ MPDEI 76_ NIDEL 81_ LELES 86_ EEERS 91_ RKIQG 96_ LLKSC 101_ GKPVE 106_ DFIQE 111_ LLAKL 116_ QGLHR 121_ QPGLR 126_ QPSPS 131_ HDGSL 136_ SPLQD 141_RARTA

Protein annotations

Protein functions:

1: Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction