Mitochondrial outer membrane protein SLC25A46 (Solute carrier family 25 member 46)
1_MHPRR 6_ PDGFD 11_ GLGYR 16_ GGARD 21_ EQGFG 26_ GAFPA 31_ RSFST 36_ GSDLG 41_ HWVTT 46_ PPDIP 51_ GSRNL 56_ HWGEK 61_ SPPYG 66_ VPTTS 71_ TPYEG 76_ PTEEP 81_ FSSGG 86_ GGSVQ 91_ GQSSE 96_ QLNRF 101_ AGFGI 106_ GLASL 111_ FTENV 116_ LAHPC 121_ IVLRR 126_ QCQVN 131_ YHAQH 136_ YHLTP 141_ FTVIN 146_ IMYSF 151_ NKTQG 156_ PRALW 161_ KGMGS 166_ TFIVQ 171_ GVTLG 176_ AEGII 181_ SEFTP 186_ LPREV 191_ LHKWS 196_ PKQIG 201_ EHLLL 206_ KSLTY 211_ VVAMP 216_ FYSAS 221_ LIETV 226_ QSEII 231_ RDNTG 236_ ILECV 241_ KEGIG 246_ RVIGM 251_ GVPHS 256_ KRLLP 261_ LLSLI 266_ FPTVL 271_ HGVLH 276_ YIISS 281_ VIQKF 286_ VLLIL 291_ KRKTY 296_ NSHLA 301_ ESTSP 306_ VQSML 311_ DAYFP 316_ ELIAN 321_ FAASL 326_ CSDVI 331_ LYPLE 336_ TVLHR 341_ LHIQG 346_ TRTII 351_ DNTDL 356_ GYEVL 361_ PINTQ 366_ YEGMR 371_ DCINT 376_ IRQEE 381_ GVFGF 386_ YKGFG 391_ AVIIQ 396_ YTLHA 401_ AVLQI 406_ TKIIY 411_STLLQ
1: Transmembrane protein of the mitochondrial outer membrane that controls mitochondrial organization (PubMed:26168012, PubMed:27390132, PubMed:27543974). May regulate the assembly of the MICOS (mitochondrial contact site and cristae organizing system) complex which is essential to the biogenesis and dynamics of mitochondrial cristae, the inwards folds of the inner mitochondrial membrane (PubMed:27390132). Through its interaction with the EMC (endoplasmic reticulum membrane protein complex), could regulate mitochondrial lipid homeostasis and thereby mitochondrial fission (PubMed:27390132)