Vesicle transport through interaction with t-SNAREs homolog 1A (Vesicle transport v-SNARE protein Vti1-like 2) (Vti1-rp2)
1_MSSDF 6_ EGYEQ 11_ DFAVL 16_ TAEIT 21_ SKIAR 26_ VPRLP 31_ PDEKK 36_ QMVAN 41_ VEKQL 46_ EEAKE 51_ LLEQM 56_ DLEVR 61_ EIPPQ 66_ SRGMY 71_ SNRMR 76_ SYKQE 81_ MGKLE 86_ TDFKR 91_ SRIAY 96_ SDEVR 101_ NELLG 106_ DDGNS 111_ SENQR 116_ AHLLD 121_ NTERL 126_ ERSSR 131_ RLEAG 136_ YQIAV 141_ ETEQI 146_ GQEML 151_ ENLSH 156_ DREKI 161_ QRARE 166_ RLRET 171_ DANLG 176_ KSSRI 181_ LTGML 186_ RRIIQ 191_ NRILL 196_ VILGI 201_ IVVIT 206_ ILMAI 211_TFSVR
1: V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non-conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be involved in increased cytokine secretion associated with cellular senescence