Nucleus accumbens-associated protein 2 (NAC-2) (BTB/POZ domain-containing protein 14A) (Repressor with BTB domain and BEN domain)
1_MSQML 6_ HIEIP 11_ NFGNT 16_ VLGCL 21_ NEQRL 26_ LGLYC 31_ DVSIV 36_ VKGQA 41_ FKAHR 46_ AVLAA 51_ SSLYF 56_ RDLFS 61_ GNSKS 66_ AFELP 71_ GSVPP 76_ ACFQQ 81_ ILSFC 86_ YTGRL 91_ TMTAS 96_ EQLVV 101_ MYTAG 106_ FLQIQ 111_ HIVER 116_ GTDLM 121_ FKVSS 126_ PHCDS 131_ QTAVI 136_ EDAGS 141_ EPQSP 146_ CNQLQ 151_ PAAAA 156_ AAPYV 161_ VSPSV 166_ PIPLL 171_ TRVKH 176_ EAMEL 181_ PPAGP 186_ GLAPK 191_ RPLET 196_ GPRDG 201_ VAVAA 206_ GAAVA 211_ AGTAP 216_ LKLPR 221_ VSYYG 226_ VPSLA 231_ TLIPG 236_ IQQMP 241_ YPQGE 246_ RTSPG 251_ ASSLP 256_ TTDSP 261_ TSYHN 266_ EEDEE 271_ DDEAY 276_ DTMVE 281_ EQYGQ 286_ MYIKA 291_ SGSYA 296_ VQEKP 301_ EPVPL 306_ ESRSC 311_ VLIRR 316_ DLVAL 321_ PASLI 326_ SQIGY 331_ RCHPK 336_ LYSEG 341_ DPGEK 346_ LELVA 351_ GSGVY 356_ ITRGQ 361_ LMNCH 366_ LCAGV 371_ KHKVL 376_ LRRLL 381_ ATFFD 386_ RNTLA 391_ NSCGT 396_ GIRSS 401_ TSDPS 406_ RKPLD 411_ SRVLN 416_ AVKLY 421_ CQNFA 426_ PSFKE 431_ SEMNV 436_ IAADM 441_ CTNAR 446_ RVRKR 451_ WLPKI 456_ KSMLP 461_ EGVEM 466_ YRTVM 471_ GSAAA 476_ SVPLD 481_ PEFPP 486_ AAAQV 491_ FEQRI 496_ YAERR 501_ GDAAT 506_ IVALR 511_ TDAVN 516_ VDLSA 521_ AANPA 526_ FDAGE 531_ EVDGA 536_ GSVIQ 541_ EVAAP 546_ EPLPA 551_ DGQSP 556_ PQPFE 561_ QGGGG 566_ PSRPQ 571_ TPAAA 576_ ARRPE 581_GTYAG
1: Functions as a transcriptional repressor through its association with the NuRD complex. Recruits the NuRD complex to the promoter of MDM2, leading to the repression of MDM2 transcription and subsequent stability of p53/TP53