Tripartite motif-containing protein 43
1_MDSDF 6_ SHAFQ 11_ KELTC 16_ VICLN 21_ YLVDP 26_ VTICC 31_ GHSFC 36_ RPCLC 41_ LSWEE 46_ AQSPA 51_ NCPAC 56_ REPSP 61_ KMDFK 66_ TNILL 71_ KNLVT 76_ IARKA 81_ SLWQF 86_ LSSEK 91_ QICGT 96_ HRQTK 101_ KMFCD 106_ MDKSL 111_ LCLLC 116_ SNSQE 121_ HGAHK 126_ HHPIE 131_ EAAEE 136_ HREKL 141_ LKQMR 146_ ILWKK 151_ IQENQ 156_ RNLYE 161_ EGRTA 166_ FLWRG 171_ NVVLR 176_ AQMIR 181_ NEYRK 186_ LHPVL 191_ HKEEK 196_ QHLER 201_ LNKEY 206_ QEIFQ 211_ QLQRS 216_ WVKMD 221_ QKSKH 226_ LKEMY 231_ QELME 236_ MCHKP 241_ DVELL 246_ QDLGD 251_ IVARS 256_ ESVLL 261_ HMPQP 266_ VNPEL 271_ TAGPI 276_ TGLVY 281_ RLNRF 286_ RVEIS 291_ FHFEV 296_ TNHNI 301_ RLFED 306_ VRSWM 311_ FRRGP 316_ LNSDR 321_ SDYFA 326_ AWGAR 331_ VFSFG 336_ KHYWE 341_ LDVDN 346_ SCDWA 351_ LGVCN 356_ NSWIR 361_ KNSTM 366_ VNSED 371_ IFLLL 376_ CLKVD 381_ NHFNL 386_ LTTSP 391_ VFPHY 396_ IEKPL 401_ GRVGV 406_ FLDFE 411_ SGSVS 416_ FLNVT 421_ KSSLI 426_ WSYPA 431_ GSLTF 436_ PVRPF 441_FYTGH
1: E3 ligase that regulates nuclear lamina integrity and the association of viral chromatin with transcriptionally-active host chromatin. Acts thereby as a herpesvirus-specific antiviral factor and mediates the ubiquitination-dependent proteasomal degradation of PCNT