Dedicator of cytokinesis protein 10 (Zizimin-3)
1_MAGER 6_ TRRFT 11_ RSLLR 16_ PGQAA 21_ ELRHS 26_ AASAA 31_ AVAVS 36_ SRQQQ 41_ RQEKP 46_ RLLEP 51_ LDYET 56_ VIEEL 61_ EKTYR 66_ NDPLQ 71_ DLLFF 76_ PSDDF 81_ SAATV 86_ SWDIR 91_ TLYST 96_ VPEDA 101_ EHKAE 106_ NLLVK 111_ EACKF 116_ YSSQW 121_ HVVNY 126_ KYEQY 131_ SGDIR 136_ QLPRA 141_ EYKPE 146_ KLPSH 151_ SFEID 156_ HEDAD 161_ KDEDT 166_ TSHSS 171_ SKGGG 176_ GAGGT 181_ GVFKS 186_ GWLYK 191_ GNFNS 196_ TVNNT 201_ VTVRS 206_ FKKRY 211_ FQLTQ 216_ LPDNS 221_ YIMNF 226_ YKDEK 231_ ISKEP 236_ KGCIF 241_ LDSCT 246_ GVVQN 251_ NRLRK 256_ YAFEL 261_ KMNDL 266_ TYFVL 271_ AAETE 276_ SDMDE 281_ WIHTL 286_ NRILQ 291_ ISPEG 296_ PLQGR 301_ RSTEL 306_ TDLGL 311_ DSLDN 316_ SVTCE 321_ CTPEE 326_ TDSSE 331_ NNLHA 336_ DFAKY 341_ LTETE 346_ DTVKT 351_ TRNME 356_ RLNLF 361_ SLDPD 366_ IDTLK 371_ LQKKD 376_ LLEPE 381_ SVIKP 386_ FEEKA 391_ AKRIM 396_ IICKA 401_ LNSNL 406_ QGCVT 411_ ENEND 416_ PITNI 421_ EPFFV 426_ SVALY 431_ DLRDS 436_ RKISA 441_ DFHVD 446_ LNHAA 451_ VRQML 456_ LGASV 461_ ALENG 466_ NIDTI 471_ TPRQS 476_ EEPHI 481_ KGLPE 486_ EWLKF 491_ PKQAV 496_ FSVSN 501_ PHSEI 506_ VLVAK 511_ IEKVL 516_ MGNIA 521_ SGAEP 526_ YIKNP 531_ DSNKY 536_ AQKIL 541_ KSNRQ 546_ FCSKL 551_ GKYRM 556_ PFAWA 561_ VRSVF 566_ KDNQG 571_ NVDRD 576_ SRFSP 581_ LFRQE 586_ SSKIS 591_ TEDLV 596_ KLVSD 601_ YRRAD 606_ RISKM 611_ QTIPG 616_ SLDIA 621_ VDNVP 626_ LEHPN 631_ CVTSS 636_ FIPVK 641_ PFNMM 646_ AQTEP 651_ TVEVE 656_ EFVYD 661_ STKYC 666_ RPYRV 671_ YKNQI 676_ YIYPK 681_ HLKYD 686_ SQKCF 691_ NKARN 696_ ITVCI 701_ EFKNS 706_ DEESA 711_ KPLKC 716_ IYGKP 721_ GGPLF 726_ TSAAY 731_ TAVLH 736_ HSQNP 741_ DFSDE 746_ VKIEL 751_ PTQLH 756_ EKHHI 761_ LFSFY 766_ HVTCD 771_ INAKA 776_ NAKKK 781_ EALET 786_ SVGYA 791_ WLPLM 796_ KHDQI 801_ ASQEY 806_ NIPIA 811_ TSLPP 816_ NYLSF 821_ QDSAS 826_ GKHGG 831_ SDIKW 836_ VDGGK 841_ PLFKV 846_ STFVV 851_ STVNT 856_ QDPHV 861_ NAFFQ 866_ ECQKR 871_ EKDMS 876_ QSPTS 881_ NFIRS 886_ CKNLL 891_ NVEKI 896_ HAIMS 901_ FLPII 906_ LNQLF 911_ KVLVQ 916_ NEEDE 921_ ITTTV 926_ TRVLT 931_ DIVAK 936_ CHEEQ 941_ LDHSV 946_ QSYIK 951_ FVFKT 956_ RACKE 961_ RTVHE 966_ ELAKN 971_ VTGLL 976_ KSNDS 981_ TTVKH 986_ VLKHS 991_ WFFFA 996_ IILKS 1001_ MAQHL 1006_ IDTNK 1011_ IQLPR 1016_ PQRFP 1021_ ESYQN 1026_ ELDNL 1031_ VMVLS 1036_ DHVIW 1041_ KYKDA 1046_ LEETR 1051_ RANHS 1056_ VARFL 1061_ KRCFT 1066_ FMDRG 1071_ YVFKM 1076_ VNNYI 1081_ SMFSS 1086_ GDLKT 1091_ LCQYK 1096_ FDFLQ 1101_ EVCQH 1106_ EHFIP 1111_ LCLPI 1116_ RSANI 1121_ PDPLT 1126_ PSEST 1131_ QELHA 1136_ SDMPE 1141_ YSVTN 1146_ EFCRK 1151_ HFLIG 1156_ ILLRE 1161_ VGFAL 1166_ QEDQD 1171_ VRHLA 1176_ LAVLK 1181_ NLMAK 1186_ HSFDD 1191_ RYREP 1196_ RKQAQ 1201_ IASLY 1206_ MPLYG 1211_ MLLDN 1216_ MPRIY 1221_ LKDLY 1226_ PFTVN 1231_ TSNQG 1236_ SRDDL 1241_ STNGG 1246_ FQSQT 1251_ AIKHA 1256_ NSVDT 1261_ SFSKD 1266_ VLNSI 1271_ AAFSS 1276_ IAIST 1281_ VNHAD 1286_ SRASL 1291_ ASLDS 1296_ NPSTN 1301_ EKSSE 1306_ KTDNC 1311_ EKIPR 1316_ PLSLI 1321_ GSTLR 1326_ FDKLD 1331_ QAETR 1336_ SLLMC 1341_ FLHIM 1346_ KTISY 1351_ ETLIA 1356_ YWQRA 1361_ PSPEV 1366_ SDFFS 1371_ ILDVC 1376_ LQNFR 1381_ YLGKR 1386_ NIIRK 1391_ IAAAF 1396_ KFVQS 1401_ TQNNG 1406_ TLKGS 1411_ NPSCQ 1416_ TSGLL 1421_ SQWMH 1426_ STSSH 1431_ EGHKQ 1436_ HRSQT 1441_ LPIIR 1446_ GKNAL 1451_ SNPKL 1456_ LQMLD 1461_ NTMTS 1466_ NSNEI 1471_ DIVHH 1476_ VDTEA 1481_ NIATE 1486_ VCLTI 1491_ LDLLS 1496_ LFTQT 1501_ HQRQL 1506_ QQCDC 1511_ QNSLM 1516_ KRVFD 1521_ TYMLF 1526_ FQVNQ 1531_ SATAL 1536_ KHVFA 1541_ SLRLF 1546_ VCKFP 1551_ SAFFQ 1556_ GPADL 1561_ CGSFC 1566_ YEVLK 1571_ CCNHR 1576_ SRSTQ 1581_ TEASA 1586_ LLYFF 1591_ MRKNF 1596_ EFNKQ 1601_ KSIVR 1606_ SHLQL 1611_ IKAVS 1616_ QLIAD 1621_ AGIGG 1626_ SRFQH 1631_ SLAIT 1636_ NNFAN 1641_ GDKQM 1646_ KNSNF 1651_ PAEVK 1656_ DLTKR 1661_ IRTVL 1666_ MATAQ 1671_ MKEHE 1676_ KDPEM 1681_ LVDLQ 1686_ YSLAN 1691_ SYAST 1696_ PELRR 1701_ TWLES 1706_ MAKIH 1711_ ARNGD 1716_ LSEAA 1721_ MCYIH 1726_ IAALI 1731_ AEYLK 1736_ RKGYW 1741_ KVEKI 1746_ CTASL 1751_ LSEDT 1756_ HPCDS 1761_ NSLLT 1766_ TPSGG 1771_ SMFSM 1776_ GWPAF 1781_ LSITP 1786_ NIKEE 1791_ GAMKE 1796_ DSGMQ 1801_ DTPYN 1806_ ENILV 1811_ EQLYM 1816_ CVEFL 1821_ WKSER 1826_ YELIA 1831_ DVNKP 1836_ IIAVF 1841_ EKQRD 1846_ FKKLS 1851_ DLYYD 1856_ IHRSY 1861_ LKVAE 1866_ VVNSE 1871_ KRLFG 1876_ RYYRV 1881_ AFYGQ 1886_ GFFEE 1891_ EEGKE 1896_ YIYKE 1901_ PKLTG 1906_ LSEIS 1911_ QRLLK 1916_ LYADK 1921_ FGADN 1926_ VKIIQ 1931_ DSNKV 1936_ NPKDL 1941_ DPKYA 1946_ YIQVT 1951_ YVTPF 1956_ FEEKE 1961_ IEDRK 1966_ TDFEM 1971_ HHNIN 1976_ RFVFE 1981_ TPFTL 1986_ SGKKH 1991_ GGVAE 1996_ QCKRR 2001_ TILTT 2006_ SHLFP 2011_ YVKKR 2016_ IQVIS 2021_ QSSTE 2026_ LNPIE 2031_ VAIDE 2036_ MSKKV 2041_ SELNQ 2046_ LCTME 2051_ EVDMI 2056_ RLQLK 2061_ LQGSV 2066_ SVKVN 2071_ AGPMA 2076_ YARAF 2081_ LEETN 2086_ AKKYP 2091_ DNQVK 2096_ LLKEI 2101_ FRQFA 2106_ DACGQ 2111_ ALDVN 2116_ ERLIK 2121_ EDQLE 2126_ YQEEL 2131_ RSHYK 2136_ DMLSE 2141_ LSTVM 2146_ NEQIT 2151_ GRDDL 2156_ SKRGV 2161_ DQTCT 2166_ RVISK 2171_ ATPAL 2176_ PTVSI 2181_SSSAE
1: Guanine nucleotide-exchange factor (GEF) that activates CDC42 and RAC1 by exchanging bound GDP for free GTP. Essential for dendritic spine morphogenesis in Purkinje cells and in hippocampal neurons, via a CDC42-mediated pathway. Sustains B-cell lymphopoiesis in secondary lymphoid tissues and regulates FCER2/CD23 expression