ELL-associated factor 2 (Testosterone-regulated apoptosis inducer and tumor suppressor protein)
1_MNSAA 6_ GFSHL 11_ DRRER 16_ VLKLG 21_ ESFEK 26_ QPRCA 31_ FHTVR 36_ YDFKP 41_ ASIDT 46_ SSEGY 51_ LEVGE 56_ GEQVT 61_ ITLPN 66_ IEGST 71_ PPVTV 76_ FKGSK 81_ KPYLK 86_ ECILI 91_ INHDT 96_ GECRL 101_ EKLSS 106_ NITVK 111_ KTRVE 116_ GSSKI 121_ QYRKE 126_ QQQQQ 131_ MWNSA 136_ RTPNL 141_ VKHSP 146_ SEDKM 151_ SPASP 156_ IDDIE 161_ RELKA 166_ EASLM 171_ DQMSS 176_ CDSSS 181_ DSKSS 186_ SSSSS 191_ EDSSS 196_ DSEDE 201_ DCKSS 206_ TSDTG 211_ NCVSG 216_ HPTMT 221_ QYRIP 226_ DIDAS 231_ HNRFR 236_ DNSGL 241_ LMNTL 246_ RNDLQ 251_LSESG
1: Acts as a transcriptional transactivator of TCEA1 elongation activity (By similarity). Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Potent inducer of apoptosis in prostatic and non-prostatic cell lines. Inhibits prostate tumor growth in vivo