TLC domain-containing protein 1 (Calfacilitin)
1_MPRLL 6_ HPALP 11_ LLLGA 16_ TLTFR 21_ ALRRA 26_ LCRLP 31_ LPVHV 36_ RADPL 41_ RTWRW 46_ HNLLV 51_ SFAHS 56_ IVSGI 61_ WALLC 66_ VWQTP 71_ DMLVE 76_ IETAW 81_ SLSGY 86_ LLVCF 91_ SAGYF 96_ IHDTV 101_ DIVAS 106_ GQTRA 111_ SWEYL 116_ VHHVM 121_ AMGAF 126_ FSGIF 131_ WSSFV 136_ GGGVL 141_ TLLVE 146_ VSNIF 151_ LTIRM 156_ MMKIS 161_ NAQDH 166_ LLYRV 171_ NKYVN 176_ LVMYF 181_ LFRLA 186_ PQAYL 191_ THFFL 196_ RYVNQ 201_ RTLGT 206_ FLLGI 211_ LLMLD 216_ VMIII 221_ YFSRL 226_ LRSDF 231_ CPEHV 236_ PKKQH 241_KDKFL
1: Regulates the composition and fluidity of the plasma membrane (PubMed:30509349). Inhibits the incorporation of membrane-fluidizing phospholipids containing omega-3 long-chain polyunsaturated fatty acids (LCPUFA) and thereby promotes membrane rigidity (PubMed:30509349). Does not appear to have any effect on LCPUFA synthesis (PubMed:30509349)