FXYD domain-containing ion transport regulator 5 (Dysadherin)
1_MSPSG 6_ RLCLL 11_ TIVGL 16_ ILPTR 21_ GQTLK 26_ DTTSS 31_ SSADS 36_ TIMDI 41_ QVPTR 46_ APDAV 51_ YTELQ 56_ PTSPT 61_ PTWPA 66_ DETPQ 71_ PQTQT 76_ QQLEG 81_ TDGPL 86_ VTDPE 91_ THKST 96_ KAAHP 101_ TDDTT 106_ TLSER 111_ PSPST 116_ DVQTD 121_ PQTLK 126_ PSGFH 131_ EDDPF 136_ FYDEH 141_ TLRKR 146_ GLLVA 151_ AVLFI 156_ TGIII 161_ LTSGK 166_ CRQLS 171_RLCRN
1: Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane (By similarity). May increase NKA activity by increasing the apparent affinity for Na(+) (PubMed:18263667). Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis (PubMed:11756660)