Carboxymethylenebutenolidase homolog (EC 3.1.-.-)
1_MANEA 6_ YPCPC 11_ DIGHR 16_ LEYGG 21_ LGREV 26_ QVEHI 31_ KAYVT 36_ KSPVD 41_ AGKAV 46_ IVIQD 51_ IFGWQ 56_ LPNTR 61_ YIADM 66_ ISGNG 71_ YTTIV 76_ PDFFV 81_ GQEPW 86_ DPSGD 91_ WSIFP 96_ EWLKT 101_ RNAQK 106_ IDREI 111_ SAILK 116_ YLKQQ 121_ CHAQK 126_ IGIVG 131_ FCWGG 136_ TAVHH 141_ LMMKY 146_ SEFRA 151_ GVSVY 156_ GIVKD 161_ SEDIY 166_ NLKNP 171_ TLFIF 176_ AENDV 181_ VIPLK 186_ DVSLL 191_ TQKLK 196_ EHCKV 201_ EYQIK 206_ TFSGQ 211_ THGFV 216_ HRKRE 221_ DCSPA 226_ DKPYI 231_ DEARR 236_NLIEW
1: Cysteine hydrolase. Can convert the prodrug olmesartan medoxomil into its pharmacologically active metabolite olmerstatan, an angiotensin receptor blocker, in liver and intestine. May also activate beta-lactam antibiotics faropenem medoxomil and lenampicillin