Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase C) (IP3 3-kinase C) (IP3K C) (InsP 3-kinase C)
1_MRRCP 6_ CRGSL 11_ NEAEA 16_ GALPA 21_ AARMG 26_ LEAPR 31_ GGRRR 36_ QPGQQ 41_ RPGPG 46_ AGAPA 51_ GRPEG 56_ GGPWA 61_ RTEGS 66_ SLHSE 71_ PERAG 76_ LGPAP 81_ GTESP 86_ QAEFW 91_ TDGQT 96_ EPAAA 101_ GLGVE 106_ TERPK 111_ QKTEP 116_ DRSSL 121_ RTHLE 126_ WSWSE 131_ LETTC 136_ LWTET 141_ GTDGL 146_ WTDPH 151_ RSDLQ 156_ FQPEE 161_ ASPWT 166_ QPGVH 171_ GPWTE 176_ LETHG 181_ SQTQP 186_ ERVKS 191_ WADNL 196_ WTHQN 201_ SSSLQ 206_ THPEG 211_ ACPSK 216_ EPSAD 221_ GSWKE 226_ LYTDG 231_ SRTQQ 236_ DIEGP 241_ WTEPY 246_ TDGSQ 251_ KKQDT 256_ EAARK 261_ QPGTG 266_ GFQIQ 271_ QDTDG 276_ SWTQP 281_ STDGS 286_ QTAPG 291_ TDCLL 296_ GEPED 301_ GPLEE 306_ PEPGE 311_ LLTHL 316_ YSHLK 321_ CSPLC 326_ PVPRL 331_ IITPE 336_ TPEPE 341_ AQPVG 346_ PPSRV 351_ EGGSG 356_ GFSSA 361_ SSFDE 366_ SEDDV 371_ VAGGG 376_ GASDP 381_ EDRSG 386_ SKPWK 391_ KLKTV 396_ LKYSP 401_ FVVSF 406_ RKHYP 411_ WVQLS 416_ GHAGN 421_ FQAGE 426_ DGRIL 431_ KRFCQ 436_ CEQRS 441_ LEQLM 446_ KDPLR 451_ PFVPA 456_ YYGMV 461_ LQDGQ 466_ TFNQM 471_ EDLLA 476_ DFEGP 481_ SIMDC 486_ KMGSR 491_ TYLEE 496_ ELVKA 501_ RERPR 506_ PRKDM 511_ YEKMV 516_ AVDPG 521_ APTPE 526_ EHAQG 531_ AVTKP 536_ RYMQW 541_ RETMS 546_ STSTL 551_ GFRIE 556_ GIKKA 561_ DGTCN 566_ TNFKK 571_ TQALE 576_ QVTKV 581_ LEDFV 586_ DGDHV 591_ ILQKY 596_ VACLE 601_ ELREA 606_ LEISP 611_ FFKTH 616_ EVVGS 621_ SLLFV 626_ HDHTG 631_ LAKVW 636_ MIDFG 641_ KTVAL 646_ PDHQT 651_ LSHRL 656_ PWAEG 661_ NREDG 666_ YLWGL 671_ DNMIC 676_LLQGL
1: Catalyzes the phosphorylation of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) into 1D-myo-inositol 1,3,4,5-tetrakisphosphate and participates to the regulation of calcium homeostasis (PubMed:11085927, PubMed:12747803). Can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate (By similarity)