Mitochondrial glycine transporter (Mitochondrial glycine transporter GlyC) (Solute carrier family 25 member 38)
1_MIQNS 6_ RPSLL 11_ QPQDV 16_ GDTVE 21_ TLMLH 26_ PVIKA 31_ FLCGS 36_ ISGTC 41_ STLLF 46_ QPLDL 51_ LKTRL 56_ QTLQP 61_ SDHGS 66_ RRVGM 71_ LAVLL 76_ KVVRT 81_ ESLLG 86_ LWKGM 91_ SPSIV 96_ RCVPG 101_ VGIYF 106_ GTLYS 111_ LKQYF 116_ LRGHP 121_ PTALE 126_ SVMLG 131_ VGSRS 136_ VAGVC 141_ MSPIT 146_ VIKTR 151_ YESGK 156_ YGYES 161_ IYAAL 166_ RSIYH 171_ SEGHR 176_ GLFSG 181_ LTATL 186_ LRDAP 191_ FSGIY 196_ LMFYN 201_ QTKNI 206_ VPHDQ 211_ VDATL 216_ IPITN 221_ FSCGI 226_ FAGIL 231_ ASLVT 236_ QPADV 241_ IKTHM 246_ QLYPL 251_ KFQWI 256_ GQAVT 261_ LIFKD 266_ YGLRG 271_ FFQGG 276_ IPRAL 281_ RRTLM 286_ AAMAW 291_ TVYEE 296_MMAKM
1: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix. Required during erythropoiesis
2: Plays a role as pro-apoptotic protein that induces caspase-dependent apoptosis