Gene name: TM4SF19

Uniprot entry:

Q96DZ7

Protein names:

Transmembrane 4 L6 family member 19 (Osteoclast maturation-associated gene 4 protein) (Tetraspan membrane protein OCTM4)

Protein sequence:

1_MVSSP 6_ CTQAS 11_ SRTCS 16_ RILGL 21_ SLGTA 26_ ALFAA 31_ GANVA 36_ LLLPN 41_ WDVTY 46_ LLRGL 51_ LGRHA 56_ MLGTG 61_ LWGGG 66_ LMVLT 71_ AAILI 76_ SLMGW 81_ RYGCF 86_ SKSGL 91_ CRSVL 96_ TALLS 101_ GGLAL 106_ LGALI 111_ CFVTS 116_ GVALK 121_ DGPFC 126_ MFDVS 131_ SFNQT 136_ QAWKY 141_ GYPFK 146_ DLHSR 151_ NYLYD 156_ RSLWN 161_ SVCLE 166_ PSAAV 171_ VWHVS 176_ LFSAL 181_ LCISL 186_ LQLLL 191_ VVVHV 196_ INSLL 201_GLFCS

Protein annotations

Protein functions:

1: Negatively regulates vacuolar (H+)-ATPase (V-ATPase) activity by interacting with members of V-ATPase V0 complex and hence inhibiting V1-V0 complex assembly. Required for multinucleation during osteoclast differentiation