RecQ-mediated genome instability protein 2 (hRMI2) (BLM-associated protein of 18 kDa) (BLAP18)
1_MAAAA 6_ DSFSG 11_ GPAGV 16_ RLPRS 21_ PPLKV 26_ LAEQL 31_ RRDAE 36_ GGPGA 41_ WRLSR 46_ AAAGR 51_ GPLDL 56_ AAVWM 61_ QGRVV 66_ MADRG 71_ EARLR 76_ DPSGD 81_ FSVRG 86_ LERVP 91_ RGRPC 96_ LVPGK 101_ YVMVM 106_ GVVQA 111_ CSPEP 116_ CLQAV 121_ KMTDL 126_ SDNPI 131_ HESMW 136_ ELEVE 141_DLHRN
1: Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates. It is required to regulate sister chromatid segregation and to limit DNA crossover. Essential for the stability, localization, and function of BLM, TOP3A, and complexes containing BLM. In the RMI complex, it is required to target BLM to chromatin and stress-induced nuclear foci and mitotic phosphorylation of BLM