F-box only protein 17 (F-box only protein 26)
1_MGARL 6_ SRRRL 11_ PADPS 16_ LALDA 21_ LPPEL 26_ LVQVL 31_ SHVPP 36_ RSLVT 41_ RCRPV 46_ CRAWR 51_ DIVDG 56_ PTVWL 61_ LQLAR 66_ DRSAE 71_ GRALY 76_ AVAQR 81_ CLPSN 86_ EDKEE 91_ FPLCA 96_ LARYC 101_ LRAPF 106_ GRNLI 111_ FNSCG 116_ EQGFR 121_ GWEVE 126_ HGGNG 131_ WAIEK 136_ NLTPV 141_ PGAPS 146_ QTCFV 151_ TSFEW 156_ CSKRQ 161_ LVDLV 166_ MEGVW 171_ QELLD 176_ SAQIE 181_ ICVAD 186_ WWGAR 191_ ENCGC 196_ VYQLR 201_ VRLLD 206_ VYEKE 211_ VVKFS 216_ ASPDP 221_ VLQWT 226_ ERGCR 231_ QVSHV 236_ FTNFG 241_ KGIRY 246_ VSFEQ 251_ YGRDV 256_ SSWVG 261_ HYGAL 266_ VTHSS 271_VRVRI
1: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Able to recognize and bind denatured glycoproteins, which are modified with complex-type oligosaccharides. Also recognizes sulfated glycans. Does not bind high-mannose glycoproteins