Arylsulfatase G (ASG) (EC 3.1.6.1) (N-sulfoglucosamine-3-sulfatase) (EC 3.1.6.15)
1_MGWLF 6_ LKVLL 11_ AGVSF 16_ SGFLY 21_ PLVDF 26_ CISGK 31_ TRGQK 36_ PNFVI 41_ ILADD 46_ MGWGD 51_ LGANW 56_ AETKD 61_ TANLD 66_ KMASE 71_ GMRFV 76_ DFHAA 81_ ASTCS 86_ PSRAS 91_ LLTGR 96_ LGLRN 101_ GVTRN 106_ FAVTS 111_ VGGLP 116_ LNETT 121_ LAEVL 126_ QQAGY 131_ VTGII 136_ GKWHL 141_ GHHGS 146_ YHPNF 151_ RGFDY 156_ YFGIP 161_ YSHDM 166_ GCTDT 171_ PGYNH 176_ PPCPA 181_ CPQGD 186_ GPSRN 191_ LQRDC 196_ YTDVA 201_ LPLYE 206_ NLNIV 211_ EQPVN 216_ LSSLA 221_ QKYAE 226_ KATQF 231_ IQRAS 236_ TSGRP 241_ FLLYV 246_ ALAHM 251_ HVPLP 256_ VTQLP 261_ AAPRG 266_ RSLYG 271_ AGLWE 276_ MDSLV 281_ GQIKD 286_ KVDHT 291_ VKENT 296_ FLWFT 301_ GDNGP 306_ WAQKC 311_ ELAGS 316_ VGPFT 321_ GFWQT 326_ RQGGS 331_ PAKQT 336_ TWEGG 341_ HRVPA 346_ LAYWP 351_ GRVPV 356_ NVTST 361_ ALLSV 366_ LDIFP 371_ TVVAL 376_ AQASL 381_ PQGRR 386_ FDGVD 391_ VSEVL 396_ FGRSQ 401_ PGHRV 406_ LFHPN 411_ SGAAG 416_ EFGAL 421_ QTVRL 426_ ERYKA 431_ FYITG 436_ GARAC 441_ DGSTG 446_ PELQH 451_ KFPLI 456_ FNLED 461_ DTAEA 466_ VPLER 471_ GGAEY 476_ QAVLP 481_ EVRKV 486_ LADVL 491_ QDIAN 496_ DNISS 501_ ADYTQ 506_ DPSVT 511_ PCCNP 516_YQIAC
1: Displays arylsulfatase activity at acidic pH towards artificial substrates, such as p-nitrocatechol sulfate and also, but with a lower activity towards p-nitrophenyl sulfate and 4-methylumbelliferyl sulfate (PubMed:18283100, PubMed:29300381). Catalyzes the hydrolysis of the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-sulfate units of heparin (PubMed:22689975)