Gene name: MVB12A

Uniprot entry:

Q96EY5

Protein names:

Multivesicular body subunit 12A (CIN85/CD2AP family-binding protein) (ESCRT-I complex subunit MVB12A) (Protein FAM125A)

Protein sequence:

1_MDPVP 6_ GTDSA 11_ PLAGL 16_ AWSSA 21_ SAPPP 26_ RGFSA 31_ ISCTV 36_ EGAPA 41_ SFGKS 46_ FAQKS 51_ GYFLC 56_ LSSLG 61_ SLENP 66_ QENVV 71_ ADIQI 76_ VVDKS 81_ PLPLG 86_ FSPVC 91_ DPMDS 96_ KASVS 101_ KKKRM 106_ CVKLL 111_ PLGAT 116_ DTAVF 121_ DVRLS 126_ GKTKT 131_ VPGYL 136_ RIGDM 141_ GGFAI 146_ WCKKA 151_ KAPRP 156_ VPKPR 161_ GLSRD 166_ MQGLS 171_ LDAAS 176_ QPSKG 181_ GLLER 186_ TASRL 191_ GSRAS 196_ TLRRN 201_ DSIYE 206_ ASSLY 211_ GISAM 216_ DGVPF 221_ TLHPR 226_ FEGKS 231_ CSPLA 236_ FSAFG 241_ DLTIK 246_ SLADI 251_ EEEYN 256_ YGFVV 261_ EKTAA 266_ARLPP

Protein annotations

Protein functions:

1: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor