Gene name: SAT2

Uniprot entry:

Q96F10

Protein names:

Thialysine N-epsilon-acetyltransferase (EC 2.3.1.-) (Diamine acetyltransferase 2) (EC 2.3.1.57) (Spermidine/spermine N(1)-acetyltransferase 2) (SSAT-2)

Protein sequence:

1_MASVR 6_ IREAK 11_ EGDCG 16_ DILRL 21_ IRELA 26_ EFEKL 31_ SDQVK 36_ ISEEA 41_ LRADG 46_ FGDNP 51_ FYHCL 56_ VAEIL 61_ PAPGK 66_ LLGPC 71_ VVGYG 76_ IYYFI 81_ YSTWK 86_ GRTIY 91_ LEDIY 96_ VMPEY 101_ RGQGI 106_ GSKII 111_ KKVAE 116_ VALDK 121_ GCSQF 126_ RLAVL 131_ DWNQR 136_ AMDLY 141_ KALGA 146_ QDLTE 151_ AEGWH 156_ FFCFQ 161_GEATR

Protein annotations

Protein functions:

1: Catalyzes the N-acetylation of the amino acid thialysine (S-(2-aminoethyl)-L-cysteine), a L-lysine analog with the 4-methylene group substituted with a sulfur (PubMed:15283699). May also catalyze acetylation of polyamines, such as norspermidine, spermidine or spermine (PubMed:12803540). However, ability to acetylate polyamines is weak, suggesting that it does not act as a diamine acetyltransferase in vivo (PubMed:15283699)