Sororin (Cell division cycle-associated protein 5) (p35)
1_MSGRR 6_ TRSGG 11_ AAQRS 16_ GPRAP 21_ SPTKP 26_ LRRSQ 31_ RKSGS 36_ ELPSI 41_ LPEIW 46_ PKTPS 51_ AAAVR 56_ KPIVL 61_ KRIVA 66_ HAVEV 71_ PAVQS 76_ PRRSP 81_ RISFF 86_ LEKEN 91_ EPPGR 96_ ELTKE 101_ DLFKT 106_ HSVPA 111_ TPTST 116_ PVPNP 121_ EAESS 126_ SKEGE 131_ LDARD 136_ LEMSK 141_ KVRRS 146_ YSRLE 151_ TLGSA 156_ STSTP 161_ GRRSC 166_ FGFEG 171_ LLGAE 176_ DLSGV 181_ SPVVC 186_ SKLTE 191_ VPRVC 196_ AKPWA 201_ PDMTL 206_ PGISP 211_ PPEKQ 216_ KRKKK 221_ KMPEI 226_ LKTEL 231_ DEWAA 236_ AMNAE 241_ FEAAE 246_QFDLL
1: Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. May antagonize the action of WAPL which stimulates cohesin dissociation from chromatin. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Required for efficient DNA double-stranded break repair