Gene name: BORCS8

Uniprot entry:

Q96FH0

Protein names:

BLOC-1-related complex subunit 8 (MEF2B neighbor)

Protein sequence:

1_MEEPE 6_ MQLKG 11_ KKVTD 16_ KFTES 21_ VYVLA 26_ NEPSV 31_ ALYRL 36_ QEHVR 41_ RSLPE 46_ LAQHK 51_ ADMQR 56_ WEEQS 61_ QGAIY 66_ TVEYA 71_ CSAVK 76_ NLVDS 81_ SVYFR 86_ SVEGL 91_ LKQAI 96_ SIRDH 101_ MNASA 106_ QGHSP 111_EEPPP

Protein annotations

Protein functions:

1: As part of the BLOC-one-related complex (BORC), it plays a role in the movement and localization of lysosomes at the cell periphery (PubMed:25898167, PubMed:38128568). Associated with the cytosolic face of lysosomes, BORC recruits ARL8B to the lysosomal membrane and couples lysosomes to microtubule plus-end-directed kinesin motors, driving lysosome movement toward the cell periphery