Post-GPI attachment to proteins factor 3 (COS16 homolog) (hCOS16) (Gene coamplified with ERBB2 protein) (PER1-like domain-containing protein 1)
1_MAGLA 6_ ARLVL 11_ LAGAA 16_ ALASG 21_ SQGDR 26_ EPVYR 31_ DCVLQ 36_ CEEQN 41_ CSGGA 46_ LNHFR 51_ SRQPI 56_ YMSLA 61_ GWTCR 66_ DDCKY 71_ ECMWV 76_ TVGLY 81_ LQEGH 86_ KVPQF 91_ HGKWP 96_ FSRFL 101_ FFQEP 106_ ASAVA 111_ SFLNG 116_ LASLV 121_ MLCRY 126_ RTFVP 131_ ASSPM 136_ YHTCV 141_ AFAWV 146_ SLNAW 151_ FWSTV 156_ FHTRD 161_ TDLTE 166_ KMDYF 171_ CASTV 176_ ILHSI 181_ YLCCV 186_ RTVGL 191_ QHPAV 196_ VSAFR 201_ ALLLL 206_ MLTVH 211_ VSYLS 216_ LIRFD 221_ YGYNL 226_ VANVA 231_ IGLVN 236_ VVWWL 241_ AWCLW 246_ NQRRL 251_ PHVRK 256_ CVVVV 261_ LLLQG 266_ LSLLE 271_ LLDFP 276_ PLFWV 281_ LDAHA 286_ IWHIS 291_ TIPVH 296_ VLFFS 301_ FLEDD 306_ SLYLL 311_KESED
1: Involved in the fatty acid remodeling steps of GPI-anchor maturation where the unsaturated acyl chain at sn-2 of inositol phosphate is replaced by a saturated stearoyl chain (PubMed:17021251, PubMed:24439110). May catalyze the first step of the fatty acid remodeling, by removing the unsaturated acyl chain at sn-2 of inositol phosphate, generating a lyso-GPI intermediate (Probable). The fatty acid remodeling steps is critical for the integration of GPI-APs into lipid rafts (By similarity)