Macrophage immunometabolism regulator
1_MEVDI 6_ NGESR 11_ STLTT 16_ LPFPG 21_ AEANS 26_ PGKAE 31_ AEKPR 36_ CSSTP 41_ CSPMR 46_ RTVSG 51_ YQILH 56_ MDSNY 61_ LVGFT 66_ TGEEL 71_ LKLAQ 76_ KCTGG 81_ EESKA 86_ EAMPS 91_ LRSKQ 96_ LDAGL 101_ ARSSR 106_ LYKTR 111_ SRYYQ 116_ PYEIP 121_ AVNGR 126_ RRRRM 131_ PSSGD 136_ KCTKS 141_ LPYEP 146_ YKALH 151_ GPLPL 156_ CLLKG 161_ KRAHS 166_ KSLDY 171_ LNLDK 176_ MIKEP 181_ ADTEV 186_ LQYQL 191_ QHLTL 196_ RGDRV 201_FARNN
1: Regulates the macrophage function, by enhancing the resolution of inflammation and wound repair functions mediated by M2 macrophages (PubMed:30659109). The regulation of macrophage function is, due at least in part, to its ability to inhibit glycolysis (PubMed:30659109). May also play a role in trafficking of proteins via its interaction with UNC119 and UNC119B cargo adapters: may help the release of UNC119 and UNC119B cargo or the recycling of UNC119 and UNC119B (PubMed:22085962). May play a role in ciliary membrane localization via its interaction with UNC119B and protein transport into photoreceptor cells (PubMed:22085962)