Gene name: MED30

Uniprot entry:

Q96HR3

Protein names:

Mediator of RNA polymerase II transcription subunit 30 (Mediator complex subunit 30) (TRAP/Mediator complex component TRAP25) (Thyroid hormone receptor-associated protein 6) (Thyroid hormone receptor-associated protein complex 25 kDa component) (Trap25)

Protein sequence:

1_MSTPP 6_ LAASG 11_ MAPGP 16_ FAGPQ 21_ AQQAA 26_ REVNT 31_ ASLCR 36_ IGQET 41_ VQDIV 46_ YRTME 51_ IFQLL 56_ RNMQL 61_ PNGVT 66_ YHTGT 71_ YQDRL 76_ TKLQD 81_ NLRQL 86_ SVLFR 91_ KLRLV 96_ YDKCN 101_ ENCGG 106_ MDPIP 111_ VEQLI 116_ PYVEE 121_ DGSKN 126_ DDRAG 131_ PPRFA 136_ SEERR 141_ EIAEV 146_ NKKLK 151_ QKNQQ 156_ LKQIM 161_ DQLRN 166_ LIWDI 171_NAMLA

Protein annotations

Protein functions:

1: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors