Receptor expression-enhancing protein 6 (Polyposis locus protein 1-like 1)
1_MDGLR 6_ QRVEH 11_ FLEQR 16_ NLVTE 21_ VLGAL 26_ EAKTG 31_ VEKRY 36_ LAAGA 41_ VTLLS 46_ LYLLF 51_ GYGAS 56_ LLCNL 61_ IGFVY 66_ PAYAS 71_ IKAIE 76_ SPSKD 81_ DDTVW 86_ LTYWV 91_ VYALF 96_ GLAEF 101_ FSDLL 106_ LSWFP 111_ FYYVG 116_ KCAFL 121_ LFCMA 126_ PRPWN 131_ GALML 136_ YQRVV 141_ RPLFL 146_ RHHGA 151_ VDRIM 156_ NDLSG 161_ RALDA 166_ AAGIT 171_ RNVLQ 176_ VLARS 181_ RAGIT 186_ PVAVA 191_ GPSTP 196_ LEADL 201_ KPSQT 206_PQPKD
1: Required for correct function and survival of retinal photoreceptors (PubMed:27889058). Required for retinal development (By similarity). In rod photoreceptors, facilitates stability and/or trafficking of guanylate cyclases and is required to maintain endoplasmic reticulum and mitochondrial homeostasis (By similarity). May play a role in clathrin-coated intracellular vesicle trafficking of proteins from the endoplasmic reticulum to the retinal rod plasma membrane (By similarity)