Zinc finger BED domain-containing protein 3 (Axin-interacting protein)
1_MRSGE 6_ PACTM 11_ DQARG 16_ LDDAA 21_ ARGGQ 26_ CPGLG 31_ PAPTP 36_ TPPGR 41_ LGAPY 46_ SEAWG 51_ YFHLA 56_ PGRPG 61_ HPSGH 66_ WATCR 71_ LCGEQ 76_ VGRGP 81_ GFHAG 86_ TSALW 91_ RHLRS 96_ AHRRE 101_ LESSG 106_ AGSSP 111_ PAAPC 116_ PPPPG 121_ PAAAP 126_ EGDWA 131_ RLLEQ 136_ MGALA 141_ VRGSR 146_ REREL 151_ ERREL 156_ AVEQG 161_ ERALE 166_ RRRRA 171_ LQEEE 176_ RAAAQ 181_ ARREL 186_ QAERE 191_ ALQAR 196_ LRDVS 201_ RREGA 206_ LGWAP 211_ AAPPP 216_ LKDDP 221_ EGDRD 226_GCVIT
1: Acts as a positive regulator in the activation of the canonical Wnt/beta-catenin signaling pathway by stabilizing cytoplasmic beta-catenin (By similarity). Involved in transcription activation of Wnt target gene expression (By similarity). Plays a role in symmetric division of blastomeres in the early stages of embryogenesis via regulation of mitotic spindle central positioning and organization of the F-actin filament network (By similarity). Plays a role in regulating the distribution of cellular organelles, via modulation of cytoskeletal dynamics and cytoplasmic lattice formation (By similarity)