Gene name: ADTRP

Uniprot entry:

Q96IZ2

Protein names:

Androgen-dependent TFPI-regulating protein (Fatty acid esters of hydroxy fatty acids hydrolase ADTRP) (FAHFA hydrolase ADTRP) (EC 3.1.-.-)

Protein sequence:

1_MTKTS 6_ TCIYH 11_ FLVLS 16_ WYTFL 21_ NYYIS 26_ QEGKD 31_ EVKPK 36_ ILANG 41_ ARWKY 46_ MTLLN 51_ LLLQT 56_ IFYGV 61_ TCLDD 66_ VLKRT 71_ KGGKD 76_ IKFLT 81_ AFRDL 86_ LFTTL 91_ AFPVS 96_ TFVFL 101_ AFWIL 106_ FLYNR 111_ DLIYP 116_ KVLDT 121_ VIPVW 126_ LNHAM 131_ HTFIF 136_ PITLA 141_ EVVLR 146_ PHSYP 151_ SKKTG 156_ LTLLA 161_ AASIA 166_ YISRI 171_ LWLYF 176_ ETGTW 181_ VYPVF 186_ AKLSL 191_ LGLAA 196_ FFSLS 201_ YVFIA 206_ SIYLL 211_ GEKLN 216_ HWKWG 221_DMRQP

Protein annotations

Protein functions:

1: Hydrolyzes bioactive fatty-acid esters of hydroxy-fatty acids (FAHFAs), but not other major classes of lipids (PubMed:27018888). Show a preference for FAHFAs with branching distal from the carboxylate head group of the lipids (PubMed:27018888). Regulates the expression and the cell-associated anticoagulant activity of the inhibitor TFPI in endothelial cells (in vitro) (PubMed:21868574)