Gene name: EPSTI1

Uniprot entry:

Q96J88

Protein names:

Epithelial-stromal interaction protein 1

Protein sequence:

1_MNTRN 6_ RVVNS 11_ GLGAS 16_ PASRP 21_ TRDPQ 26_ DPSGR 31_ QGELS 36_ PVEDQ 41_ REGLE 46_ AAPKG 51_ PSRES 56_ VVHAG 61_ QRRTS 66_ AYTLI 71_ APNIN 76_ RRNEI 81_ QRIAE 86_ QELAN 91_ LEKWK 96_ EQNRA 101_ KPVHL 106_ VPRRL 111_ GGSQS 116_ ETEVR 121_ QKQQL 126_ QLMQS 131_ KYKQK 136_ LKREE 141_ SVRIK 146_ KEAEE 151_ AELQK 156_ MKAIQ 161_ REKSN 166_ KLEEK 171_ KRLQE 176_ NLRRE 181_ AFREH 186_ QQYKT 191_ AEFLS 196_ KLNTE 201_ SPDRS 206_ ACQSA 211_ VCGPQ 216_ SSTWK 221_ LPILP 226_ RDHSW 231_ ARSWA 236_ YRDSL 241_ KAEEN 246_ RKLQK 251_ MKDEQ 256_ HQKSE 261_ LLELK 266_ RQQQE 271_ QERAK 276_ IHQTE 281_ HRRVN 286_ NAFLD 291_ RLQGK 296_ SQPGG 301_ LEQSG 306_ GCWNM 311_NSGNS

Protein annotations

Protein functions:

1: Plays a role in M1 macrophage polarization and is required for the proper regulation of gene expression during M1 versus M2 macrophage differentiation (By similarity). Might play a role in RELA/p65 and STAT1 phosphorylation and nuclear localization upon activation of macrophages (By similarity)