Syndetin (Coiled-coil domain-containing protein 132) (EARP/GARPII complex subunit VPS50)
1_MQKIK 6_ SLMTR 11_ QGLKS 16_ PQESL 21_ SDLGA 26_ IESLR 31_ VPGKE 36_ EFREL 41_ REQPS 46_ DPQAE 51_ QELIN 56_ SIEQV 61_ YFSVD 66_ SFDIV 71_ KYELE 76_ KLPPV 81_ LNLQE 86_ LEAYR 91_ DKLKQ 96_ QQAAV 101_ SKKVA 106_ DLILE 111_ KQPAY 116_ VKELE 121_ RVTSL 126_ QTGLQ 131_ LAAVI 136_ CTNGR 141_ RHLNI 146_ AKEGF 151_ TQASL 156_ GLLAN 161_ QRKRQ 166_ LLIGL 171_ LKSLR 176_ TIKTL 181_ QRTDV 186_ RLSEM 191_ LEEED 196_ YPGAI 201_ QLCLE 206_ CQKAA 211_ STFKH 216_ YSCIS 221_ ELNSK 226_ LQDTL 231_ EQIEE 236_ QLDVA 241_ LSKIC 246_ KNFDI 251_ NHYTK 256_ VQQAY 261_ RLLGK 266_ TQTAM 271_ DQLHM 276_ HFTQA 281_ IHNTV 286_ FQVVL 291_ GYVEL 296_ CAGNT 301_ DTKFQ 306_ KLQYK 311_ DLCTH 316_ VTPDS 321_ YIPCL 326_ ADLCK 331_ ALWEV 336_ MLSYY 341_ RTMEW 346_ HEKHD 351_ NEDTA 356_ SASEG 361_ SNMIG 366_ TEETN 371_ FDRGY 376_ IKKKL 381_ EHGLT 386_ RIWQD 391_ VQLKV 396_ KTYLL 401_ GTDLS 406_ IFKYD 411_ DFIFV 416_ LDIIS 421_ RLMQV 426_ GEEFC 431_ GSKSE 436_ VLQES 441_ IRKQS 446_ VNYFK 451_ NYHRT 456_ RLDEL 461_ RMFLE 466_ NETWE 471_ LCPVK 476_ SNFSI 481_ LQLHE 486_ FKFME 491_ QSRSP 496_ SVSPS 501_ KQPVS 506_ TSSKT 511_ VTLFE 516_ QYCSG 521_ GNPFE 526_ IQANH 531_ KDEET 536_ EDVLA 541_ SNGYE 546_ SDEQE 551_ KSAYQ 556_ EYDSD 561_ SDVPE 566_ ELKRD 571_ YVDEQ 576_ TGDGP 581_ VKSVS 586_ RETLK 591_ SRKKS 596_ DYSLN 601_ KVNAP 606_ ILTNT 611_ TLNVI 616_ RLVGK 621_ YMQMM 626_ NILKP 631_ IAFDV 636_ IHFMS 641_ QLFDY 646_ YLYAI 651_ YTFFG 656_ RNDSL 661_ ESTGL 666_ GLSSS 671_ RLRTT 676_ LNRIQ 681_ ESLID 686_ LEVSA 691_ DPTAT 696_ LTAAE 701_ ERKEK 706_ VPSPH 711_ LSHLV 716_ VLTSG 721_ DTLYG 726_ LAERV 731_ VATES 736_ LVFLA 741_ EQFEF 746_ LQPHL 751_ DAVMP 756_ AVKKP 761_ FLQQF 766_ YSQTV 771_ STASE 776_ LRKPI 781_ YWIVA 786_ GKALD 791_ YEQML 796_ LLMAN 801_ VKWDV 806_ KEIMS 811_ QHNIY 816_ VDALL 821_ KEFEQ 826_ FNRRL 831_ NEVSK 836_ RVRIP 841_ LPVSN 846_ ILWEH 851_ CIRLA 856_ NRTIV 861_ EGYAN 866_ VKKCS 871_ NEGRA 876_ LMQLD 881_ FQQFL 886_ MKLEK 891_ LTDIR 896_ PIPDK 901_ EFVET 906_ YIKAY 911_ YLTEN 916_ DMERW 921_ IKEHR 926_ EYSTK 931_ QLTNL 936_ VNVCL 941_ GSHIN 946_ KKARQ 951_ KLLAA 956_IDDID
1: Acts as a component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane. Within the EARP complex, required to tether the complex to recycling endosomes. Not involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN)