Engulfment and cell motility protein 2 (Protein ced-12 homolog A) (hCed-12A)
1_MPPPS 6_ DIVKV 11_ AIEWP 16_ GANAQ 21_ LLEID 26_ QKRPL 31_ ASIIK 36_ EVCDG 41_ WSLPN 46_ PEYYT 51_ LRYAD 56_ GPQLY 61_ ITEQT 66_ RSDIK 71_ NGTIL 76_ QLAIS 81_ PSRAA 86_ RQLME 91_ RTQSS 96_ NMETR 101_ LDAMK 106_ ELAKL 111_ SADVT 116_ FATEF 121_ INMDG 126_ IIVLT 131_ RLVES 136_ GTKLL 141_ SHYSE 146_ MLAFT 151_ LTAFL 156_ ELMDH 161_ GIVSW 166_ DMVSI 171_ TFIKQ 176_ IAGYV 181_ SQPMV 186_ DVSIL 191_ QRSLA 196_ ILESM 201_ VLNSQ 206_ SLYQK 211_ IAEEI 216_ TVGQL 221_ ISHLQ 226_ VSNQE 231_ IQTYA 236_ IALIN 241_ ALFLK 246_ APEDK 251_ RQDMA 256_ NAFAQ 261_ KHLRS 266_ IILNH 271_ VIRGN 276_ RPIKT 281_ EMAHQ 286_ LYVLQ 291_ VLTFN 296_ LLEER 301_ MMTKM 306_ DPNDQ 311_ AQRDI 316_ IFELR 321_ RIAFD 326_ AESDP 331_ SNAPG 336_ SGTEK 341_ RKAMY 346_ TKDYK 351_ MLGFT 356_ NHINP 361_ AMDFT 366_ QTPPG 371_ MLALD 376_ NMLYL 381_ AKVHQ 386_ DTYIR 391_ IVLEN 396_ SSRED 401_ KHECP 406_ FGRSA 411_ IELTK 416_ MLCEI 421_ LQVGE 426_ LPNEG 431_ RNDYH 436_ PMFFT 441_ HDRAF 446_ EELFG 451_ ICIQL 456_ LNKTW 461_ KEMRA 466_ TAEDF 471_ NKVMQ 476_ VVREQ 481_ ITRAL 486_ PSKPN 491_ SLDQF 496_ KSKLR 501_ SLSYS 506_ EILRL 511_ RQSER 516_ MSQDD 521_ FQSPP 526_ IVELR 531_ EKIQP 536_ EILEL 541_ IKQQR 546_ LNRLC 551_ EGSSF 556_ RKIGN 561_ RRRQE 566_ RFWYC 571_ RLALN 576_ HKVLH 581_ YGDLD 586_ DNPQG 591_ EVTFE 596_ SLQEK 601_ IPVAD 606_ IKAIV 611_ TGKDC 616_ PHMKE 621_ KSALK 626_ QNKEV 631_ LELAF 636_ SILYD 641_ PDETL 646_ NFIAP 651_ NKYEY 656_ CIWID 661_ GLSAL 666_ LGKDM 671_ SSELT 676_ KSDLD 681_ TLLSM 686_ EMKLR 691_ LLDLE 696_ NIQIP 701_ EAPPP 706_ IPKEP 711_SSYDF
1: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1