Ligand-dependent corepressor (LCoR) (Mblk1-related protein 2)
1_MQRMI 6_ QQFAA 11_ EYTSK 16_ NSSTQ 21_ DPSQP 26_ NSTKN 31_ QSLPK 36_ ASPVT 41_ TSPTA 46_ ATTQN 51_ PVLSK 56_ LLMAD 61_ QDSPL 66_ DLTVR 71_ KSQSE 76_ PSEQD 81_ GVLDL 86_ STKKS 91_ PCAGS 96_ TSLSH 101_ SPGCS 106_ STQGN 111_ GRPGR 116_ PSQYR 121_ PDGLR 126_ SGDGV 131_ PPRSL 136_ QDGTR 141_ EGFGH 146_ STSLK 151_ VPLAR 156_ SLQIS 161_ EELLS 166_ RNQLS 171_ TAASL 176_ GPSGL 181_ QNHGQ 186_ HLILS 191_ REASW 196_ AKPHY 201_ EFNLS 206_ RMKFR 211_ GNGAL 216_ SNISD 221_ LPFLA 226_ ENSAF 231_ PKMAL 236_ QAKQD 241_ GKKDV 246_ SHSSP 251_ VDLKI 256_ PQVRG 261_ MDLSW 266_ ESRTG 271_ DQYSY 276_ SSLVM 281_ GSQTE 286_ SALSK 291_ KLRAI 296_ LPKQS 301_ RKSML 306_ DAGPD 311_ SWGSD 316_ AEQST 321_ SGQPY 326_ PTSDQ 331_ EGDPG 336_ SKQPR 341_ KKRGR 346_ YRQYN 351_ SEILE 356_ EAISV 361_ VMSGK 366_ MSVSK 371_ AQSIY 376_ GIPHS 381_ TLEYK 386_ VKERL 391_ GTLKN 396_ PPKKK 401_ MKLMR 406_ SEGPD 411_ VSVKI 416_ ELDPQ 421_ GEAAQ 426_SANES
1: May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3' (By similarity). Repressor of ligand-dependent transcription activation by target nuclear receptors. Repressor of ligand-dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR