Protein maelstrom homolog
1_MPNRK 6_ ASRNA 11_ YYFFV 16_ QEKIP 21_ ELRRR 26_ GLPVA 31_ RVADA 36_ IPYCS 41_ SDWAL 46_ LREEE 51_ KEKYA 56_ EMARE 61_ WRAAQ 66_ GKDPG 71_ PSEKQ 76_ KPVFT 81_ PLRRP 86_ GMLVP 91_ KQNVS 96_ PPDMS 101_ ALSLK 106_ GDQAL 111_ LGGIF 116_ YFLNI 121_ FSHGE 126_ LPPHC 131_ EQRFL 136_ PCEIG 141_ CVKYS 146_ LQEGI 151_ MADFH 156_ SFINP 161_ GEIPR 166_ GFRFH 171_ CQAAS 176_ DSSHK 181_ IPISN 186_ FERGH 191_ NQATV 196_ LQNLY 201_ RFIHP 206_ NPGNW 211_ PPIYC 216_ KSDDR 221_ TRVNW 226_ CLKHM 231_ AKASE 236_ IRQDL 241_ QLLTV 246_ EDLVV 251_ GIYQQ 256_ KFLKE 261_ PSKTW 266_ IRSLL 271_ DVAMW 276_ DYSSN 281_ TRCKW 286_ HEEND 291_ ILFCA 296_ LAVCK 301_ KIAYC 306_ ISNSL 311_ ATLFG 316_ IQLTE 321_ AHVPL 326_ QDYEA 331_ SNSVT 336_ PKMVV 341_ LDAGR 346_ YQKLR 351_ VGSSG 356_ FSHFN 361_ SSNEE 366_ QRSNT 371_ PIGDY 376_ PSRAK 381_ ISGQN 386_ SSVRG 391_ RGITR 396_ LLESI 401_ SNSSS 406_ NIHKF 411_ SNCDT 416_ SLSPY 421_ MSQKD 426_GYKSF
1: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for the localization of germ-cell factors to the meiotic nuage (By similarity)