Gene name: CLPTM1L

Uniprot entry:

Q96KA5

Protein names:

Cleft lip and palate transmembrane protein 1-like protein (CLPTM1-like protein) (Cisplatin resistance-related protein 9) (CRR9p)

Protein sequence:

1_MWSGR 6_ SSFTS 11_ LVVGV 16_ FVVYV 21_ VHTCW 26_ VMYGI 31_ VYTRP 36_ CSGDA 41_ NCIQP 46_ YLARR 51_ PKLQL 56_ SVYTT 61_ TRSHL 66_ GAENN 71_ IDLVL 76_ NVEDF 81_ DVESK 86_ FERTV 91_ NVSVP 96_ KKTRN 101_ NGTLY 106_ AYIFL 111_ HHAGV 116_ LPWHD 121_ GKQVH 126_ LVSPL 131_ TTYMV 136_ PKPEE 141_ INLLT 146_ GESDT 151_ QQIEA 156_ EKKPT 161_ SALDE 166_ PVSHW 171_ RPRLA 176_ LNVMA 181_ DNFVF 186_ DGSSL 191_ PADVH 196_ RYMKM 201_ IQLGK 206_ TVHYL 211_ PILFI 216_ DQLSN 221_ RVKDL 226_ MVINR 231_ STTEL 236_ PLTVS 241_ YDKVS 246_ LGRLR 251_ FWIHM 256_ QDAVY 261_ SLQQF 266_ GFSEK 271_ DADEV 276_ KGIFV 281_ DTNLY 286_ FLALT 291_ FFVAA 296_ FHLLF 301_ DFLAF 306_ KNDIS 311_ FWKKK 316_ KSMIG 321_ MSTKA 326_ VLWRC 331_ FSTVV 336_ IFLFL 341_ LDEQT 346_ SLLVL 351_ VPAGV 356_ GAAIE 361_ LWKVK 366_ KALKM 371_ TIFWR 376_ GLMPE 381_ FQFGT 386_ YSESE 391_ RKTEE 396_ YDTQA 401_ MKYLS 406_ YLLYP 411_ LCVGG 416_ AVYSL 421_ LNIKY 426_ KSWYS 431_ WLINS 436_ FVNGV 441_ YAFGF 446_ LFMLP 451_ QLFVN 456_ YKLKS 461_ VAHLP 466_ WKAFT 471_ YKAFN 476_ TFIDD 481_ VFAFI 486_ ITMPT 491_ SHRLA 496_ CFRDD 501_ VVFLV 506_ YLYQR 511_ WLYPV 516_ DKRRV 521_ NEFGE 526_ SYEEK 531_ATRAP

Protein annotations

Protein functions:

1: Scramblase that mediates the translocation of glucosaminylphosphatidylinositol (alpha-D-GlcN-(1-6)-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol, GlcN-PI) across the endoplasmic reticulum (ER) membrane, from the cytosolic leaflet to the luminal leaflet of the ER membrane, where it participates in the biosynthesis of glycosylphosphatidylinositol (GPI) (PubMed:35344438). GPI is a lipid glycoconjugate involved in post-translational modification of proteins (PubMed:35344438). Can also translocate 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) (phosphatidylinositol or PI), as well as several other phospholipids (1,2-diacyl-sn-glycero-3-phosphocholine, 1,2-diacyl-sn-glycero-3-phosphoethanolamine), and N-acetylglucosaminylphosphatidylinositol (GlcNAc-PI) in vitro (PubMed:35344438)