Multiple epidermal growth factor-like domains protein 10 (Multiple EGF-like domains protein 10)
1_MVISL 6_ NSCLS 11_ FICLL 16_ LCHWI 21_ GTASP 26_ LNLED 31_ PNVCS 36_ HWESY 41_ SVTVQ 46_ ESYPH 51_ PFDQI 56_ YYTSC 61_ TDILN 66_ WFKCT 71_ RHRVS 76_ YRTAY 81_ RHGEK 86_ TMYRR 91_ KSQCC 96_ PGFYE 101_ SGEMC 106_ VPHCA 111_ DKCVH 116_ GRCIA 121_ PNTCQ 126_ CEPGW 131_ GGTNC 136_ SSACD 141_ GDHWG 146_ PHCTS 151_ RCQCK 156_ NGALC 161_ NPITG 166_ ACHCA 171_ AGFRG 176_ WRCED 181_ RCEQG 186_ TYGND 191_ CHQRC 196_ QCQNG 201_ ATCDH 206_ VTGEC 211_ RCPPG 216_ YTGAF 221_ CEDLC 226_ PPGKH 231_ GPQCE 236_ QRCPC 241_ QNGGV 246_ CHHVT 251_ GECSC 256_ PSGWM 261_ GTVCG 266_ QPCPE 271_ GRFGK 276_ NCSQE 281_ CQCHN 286_ GGTCD 291_ AATGQ 296_ CHCSP 301_ GYTGE 306_ RCQDE 311_ CPVGT 316_ YGVLC 321_ AETCQ 326_ CVNGG 331_ KCYHV 336_ SGACL 341_ CEAGF 346_ AGERC 351_ EARLC 356_ PEGLY 361_ GIKCD 366_ KRCPC 371_ HLENT 376_ HSCHP 381_ MSGEC 386_ ACKPG 391_ WSGLY 396_ CNETC 401_ SPGFY 406_ GEACQ 411_ QICSC 416_ QNGAD 421_ CDSVT 426_ GKCTC 431_ APGFK 436_ GIDCS 441_ TPCPL 446_ GTYGI 451_ NCSSR 456_ CGCKN 461_ DAVCS 466_ PVDGS 471_ CTCKA 476_ GWHGV 481_ DCSIR 486_ CPSGT 491_ WGFGC 496_ NLTCQ 501_ CLNGG 506_ ACNTL 511_ DGTCT 516_ CAPGW 521_ RGEKC 526_ ELPCQ 531_ DGTYG 536_ LNCAE 541_ RCDCS 546_ HADGC 551_ HPTTG 556_ HCRCL 561_ PGWSG 566_ VHCDS 571_ VCAEG 576_ RWGPN 581_ CSLPC 586_ YCKNG 591_ ASCSP 596_ DDGIC 601_ ECAPG 606_ FRGTT 611_ CQRIC 616_ SPGFY 621_ GHRCS 626_ QTCPQ 631_ CVHSS 636_ GPCHH 641_ ITGLC 646_ DCLPG 651_ FTGAL 656_ CNEVC 661_ PSGRF 666_ GKNCA 671_ GICTC 676_ TNNGT 681_ CNPID 686_ RSCQC 691_ YPGWI 696_ GSDCS 701_ QPCPP 706_ AHWGP 711_ NCIHT 716_ CNCHN 721_ GAFCS 726_ AYDGE 731_ CKCTP 736_ GWTGL 741_ YCTQR 746_ CPLGF 751_ YGKDC 756_ ALICQ 761_ CQNGA 766_ DCDHI 771_ SGQCT 776_ CRTGF 781_ MGRHC 786_ EQKCP 791_ SGTYG 796_ YGCRQ 801_ ICDCL 806_ NNSTC 811_ DHITG 816_ TCYCS 821_ PGWKG 826_ ARCDQ 831_ AGVII 836_ VGNLN 841_ SLSRT 846_ STALP 851_ ADSYQ 856_ IGAIA 861_ GIIIL 866_ VLVVL 871_ FLLAL 876_ FIIYR 881_ HKQKG 886_ KESSM 891_ PAVTY 896_ TPAMR 901_ VVNAD 906_ YTISG 911_ TLPHS 916_ NGGNA 921_ NSHYF 926_ TNPSY 931_ HTLTQ 936_ CATSP 941_ HVNNR 946_ DRMTV 951_ TKSKN 956_ NQLFV 961_ NLKNV 966_ NPGKR 971_ GPVGD 976_ CTGTL 981_ PADWK 986_ HGGYL 991_ NELGA 996_ FGLDR 1001_ SYMGK 1006_ SLKDL 1011_ GKNSE 1016_ YNSSN 1021_ CSLSS 1026_ SENPY 1031_ ATIKD 1036_ PPVLI 1041_ PKSSE 1046_ CGYVE 1051_ MKSPA 1056_ RRDSP 1061_ YAEIN 1066_ NSTSA 1071_ NRNVY 1076_ EVEPT 1081_ VSVVQ 1086_ GVFSN 1091_ NGRLS 1096_ QDPYD 1101_ LPKNS 1106_ HIPCH 1111_ YDLLP 1116_ VRDSS 1121_ SSPKQ 1126_ EDSGG 1131_SSSNS
1: Membrane receptor involved in phagocytosis by macrophages and astrocytes of apoptotic cells. Receptor for C1q, an eat-me signal, that binds phosphatidylserine expressed on the surface of apoptotic cells (PubMed:27170117). Cooperates with ABCA1 within the process of engulfment. Promotes the formation of large intracellular vacuoles and may be responsible for the uptake of amyloid-beta peptides (PubMed:17643423, PubMed:20828568). Necessary for astrocyte-dependent apoptotic neuron clearance in the developing cerebellum (PubMed:27170117). Plays role in muscle cell proliferation, adhesion and motility. Is also an essential factor in the regulation of myogenesis. Controls the balance between skeletal muscle satellite cells proliferation and differentiation through regulation of the notch signaling pathway (PubMed:28498977, Ref.16). May also function in the mosaic spacing of specific neuron subtypes in the retina through homotypic retinal neuron repulsion. Mosaics provide a mechanism to distribute each cell type evenly across the retina, ensuring that all parts of the visual field have access to a full set of processing elements (PubMed:17498693, PubMed:17643423, PubMed:20828568, PubMed:22101682, PubMed:27170117, PubMed:28498977)