F-actin-capping protein subunit alpha-3 (CapZ alpha-3) (CP-alpha-3) (Germ cell-specific protein 3)
1_MTLSV 6_ LSRKD 11_ KERVI 16_ RRLLL 21_ QAPPG 26_ EFVNA 31_ FDDLC 36_ LLIRD 41_ EKLMH 46_ HQGEC 51_ AGHQH 56_ CQKYS 61_ VPLCI 66_ DGNPV 71_ LLSHH 76_ NVMGD 81_ YRFFD 86_ HQSKL 91_ SFKYD 96_ LLQNQ 101_ LKDIQ 106_ SHGII 111_ QNEAE 116_ YLRVV 121_ LLCAL 126_ KLYVN 131_ DHYPK 136_ GNCNM 141_ LRKTV 146_ KSKEY 151_ LIACI 156_ EDHNY 161_ ETGEC 166_ WNGLW 171_ KSKWI 176_ FQVNP 181_ FLTQV 186_ TGRIF 191_ VQAHF 196_ FRCVN 201_ LHIEI 206_ SKDLK 211_ ESLEI 216_ VNQAQ 221_ LALSF 226_ ARLVE 231_ EQENK 236_ FQAAV 241_ LEELQ 246_ ELSNE 251_ ALRKI 256_ LRRDL 261_ PVTRT 266_ LIDWH 271_ RILSD 276_ LNLVM 281_ YPKLG 286_ YVIYS 291_RSVLC
1: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity)