Gene name: SENP8

Uniprot entry:

Q96LD8

Protein names:

Sentrin-specific protease 8 (EC 3.4.22.-) (Deneddylase-1) (NEDD8-specific protease 1) (Protease, cysteine 2) (Sentrin/SUMO-specific protease SENP8)

Protein sequence:

1_MDPVV 6_ LSYMD 11_ SLLRQ 16_ SDVSL 21_ LDPPS 26_ WLNDH 31_ IIGFA 36_ FEYFA 41_ NSQFH 46_ DCSDH 51_ VSFIS 56_ PEVTQ 61_ FIKCT 66_ SNPAE 71_ IAMFL 76_ EPLDL 81_ PNKRV 86_ VFLAI 91_ NDNSN 96_ QAAGG 101_ THWSL 106_ LVYLQ 111_ DKNSF 116_ FHYDS 121_ HSRSN 126_ SVHAK 131_ QVAEK 136_ LEAFL 141_ GRKGD 146_ KLAFV 151_ EEKAP 156_ AQQNS 161_ YDCGM 166_ YVICN 171_ TEALC 176_ QNFFR 181_ QQTES 186_ LLQLL 191_ TPAYI 196_ TKKRG 201_ EWKDL 206_ITTLA

Protein annotations

Protein functions:

1: Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53