Gene name: SPATA33

Uniprot entry:

Q96N06

Protein names:

Spermatogenesis-associated protein 33

Protein sequence:

1_MVTHA 6_ AGART 11_ FCEEQ 16_ KKGST 21_ YSVPK 26_ SKEKL 31_ MEKHS 36_ QEARQ 41_ ADRES 46_ EKPVD 51_ SLHPG 56_ AGTAK 61_ HPPPA 66_ ASLEE 71_ KPDVK 76_ QKSSR 81_ KKVVV 86_ PQIII 91_ TRASN 96_ ETLVS 101_ CSSSG 106_ SDQQR 111_ TIREP 116_ EDWGP 121_ YRRHR 126_ NPSTA 131_DAYNS

Protein annotations

Protein functions:

1: Plays an important role in sperm motility and male fertility (By similarity). Required for sperm midpiece flexibility and for the localization of sperm calcineurin to the mitochondria (By similarity). Promotes mitophagy as well as acts as an autophagy mediator in male germline cells (By similarity). Links damaged mitochondria to autophagosomes via its binding to the outer mitochondrial membrane protein VDAC2, as well as to key autophagy machinery component ATG16L1 (By similarity)