Gene name: MBOAT7

Uniprot entry:

Q96N66

Protein names:

Lysophospholipid acyltransferase 7 (LPLAT 7) (EC 2.3.1.-) (1-acylglycerophosphatidylinositol O-acyltransferase) (Bladder and breast carcinoma-overexpressed gene 1 protein) (Leukocyte receptor cluster member 4) (Lysophosphatidylinositol acyltransferase) (LPIAT) (Lyso-PI acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 7) (O-acyltransferase domain-containing protein 7) (h-mboa-7)

Protein sequence:

1_MSPEE 6_ WTYLV 11_ VLLIS 16_ IPIGF 21_ LFKKA 26_ GPGLK 31_ RWGAA 36_ AVGLG 41_ LTLFT 46_ CGPHT 51_ LHSLV 56_ TILGT 61_ WALIQ 66_ AQPCS 71_ CHALA 76_ LAWTF 81_ SYLLF 86_ FRALS 91_ LLGLP 96_ TPTPF 101_ TNAVQ 106_ LLLTL 111_ KLVSL 116_ ASEVQ 121_ DLHLA 126_ QRKEM 131_ ASGFS 136_ KGPTL 141_ GLLPD 146_ VPSLM 151_ ETLSY 156_ SYCYV 161_ GIMTG 166_ PFFRY 171_ RTYLD 176_ WLEQP 181_ FPGAV 186_ PSLRP 191_ LLRRA 196_ WPAPL 201_ FGLLF 206_ LLSSH 211_ LFPLE 216_ AVRED 221_ AFYAR 226_ PLPAR 231_ LFYMI 236_ PVFFA 241_ FRMRF 246_ YVAWI 251_ AAECG 256_ CIAAG 261_ FGAYP 266_ VAAKA 271_ RAGGG 276_ PTLQC 281_ PPPSS 286_ PEKAA 291_ SLEYD 296_ YETIR 301_ NIDCY 306_ STDFC 311_ VRVRD 316_ GMRYW 321_ NMTVQ 326_ WWLAQ 331_ YIYKS 336_ APARS 341_ YVLRS 346_ AWTML 351_ LSAYW 356_ HGLHP 361_ GYYLS 366_ FLTIP 371_ LCLAA 376_ EGRLE 381_ SALRG 386_ RLSPG 391_ GQKAW 396_ DWVHW 401_ FLKMR 406_ AYDYM 411_ CMGFV 416_ LLSLA 421_ DTLRY 426_ WASIY 431_ FCIHF 436_ LALAA 441_ LGLGL 446_ ALGGG 451_ SPSRR 456_ KAASQ 461_ PTSLA 466_PEKLR

Protein annotations

Protein functions:

1: Acyltransferase which catalyzes the transfer of an acyl group from an acyl-CoA to a lysophosphatidylinositol (1-acylglycerophosphatidylinositol or LPI) leading to the production of a phosphatidylinositol (1,2-diacyl-sn-glycero-3-phosphoinositol or PI) and participates in the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle (PubMed:18094042, PubMed:18772128). Prefers arachidonoyl-CoA as the acyl donor, thus contributing to the regulation of free levels arachidonic acid in cell (PubMed:18094042, PubMed:18772128). In liver, participates in the regulation of triglyceride metabolism through the phosphatidylinositol acyl-chain remodeling regulation (PubMed:32253259)