Zinc finger protein 830 (Coiled-coil domain-containing protein 16)
1_MASSA 6_ SARTP 11_ AGKRV 16_ INQEE 21_ LRRLM 26_ KEKQR 31_ LSTSR 36_ KRIES 41_ PFAKY 46_ NRLGQ 51_ LSCAL 56_ CNTPV 61_ KSELL 66_ WQTHV 71_ LGKQH 76_ REKVA 81_ ELKGA 86_ KEASQ 91_ GSSAS 96_ SAPHS 101_ VKRKA 106_ PDADD 111_ QDVKR 116_ AKATL 121_ VPQVQ 126_ PSTSA 131_ WTTNF 136_ DKIGK 141_ EFIRA 146_ TPSKP 151_ SGLSL 156_ LPDYE 161_ DEEEE 166_ EEEEE 171_ GDGER 176_ KRGDA 181_ SKPLS 186_ DAQGK 191_ EHSVS 196_ SSREV 201_ TSSVL 206_ PNDFF 211_ STNPP 216_ KAPII 221_ PHSGS 226_ IEKAE 231_ IHEKV 236_ VERRE 241_ NTAEA 246_ LPEGF 251_ FDDPE 256_ VDARV 261_ RKVDA 266_ PKDQM 271_ DKEWD 276_ EFQKA 281_ MRQVN 286_ TISEA 291_ IVAEE 296_ DEEGR 301_ LDRQI 306_ GEIDE 311_ QIECY 316_ RRVEK 321_ LRNRQ 326_ DEIKN 331_ KLKEI 336_ LTIKE 341_ LQKKE 346_ EENAD 351_ SDDEG 356_ ELQDL 361_ LSQDW 366_RVKGA
1: May play a role in pre-mRNA splicing as component of the spliceosome (PubMed:25599396). Acts as an important regulator of the cell cycle that participates in the maintenance of genome integrity. During cell cycle progression in embryonic fibroblast, prevents replication fork collapse, double-strand break formation and cell cycle checkpoint activation. Controls mitotic cell cycle progression and cell survival in rapidly proliferating intestinal epithelium and embryonic stem cells. During the embryo preimplantation, controls different aspects of M phase. During early oocyte growth, plays a role in oocyte survival by preventing chromosomal breaks formation, activation of TP63 and reduction of transcription (By similarity)