Regulation of nuclear pre-mRNA domain-containing protein 1A (Cyclin-dependent kinase inhibitor 2B-related protein) (p15INK4B-related protein)
1_MSAFS 6_ EAALE 11_ KKLSE 16_ LSNSQ 21_ QSVQT 26_ LSLWL 31_ IHHRK 36_ HSRPI 41_ VTVWE 46_ RELRK 51_ AKPNR 56_ KLTFL 61_ YLAND 66_ VIQNS 71_ KRKGP 76_ EFTKD 81_ FAPVI 86_ VEAFK 91_ HVSSE 96_ TDESC 101_ KKHLG 106_ RVLSI 111_ WEERS 116_ VYEND 121_ VLEQL 126_ KQALY 131_ GDKKP 136_ RKRTY 141_ EQIKV 146_ DENEN 151_ CSSLG 156_ SPSEP 161_ PQTLD 166_ LVRAL 171_ QDLEN 176_ AASGD 181_ AAVHQ 186_ RIASL 191_ PVEVQ 196_ EVSLL 201_ DKITD 206_ KESGE 211_ RLSKM 216_ VEDAC 221_ MLLAD 226_ YNGRL 231_ AAEID 236_ DRKQL 241_ TRMLA 246_ DFLRC 251_ QKEAL 256_ AEKEH 261_ KLEEY 266_ KRKLA 271_ RVSLV 276_ RKELR 281_ SRIQS 286_ LPDLS 291_ RLPNV 296_ TGSHM 301_ HLPFA 306_GDIYS
1: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle